{
  "abstract": "A nosocomial outbreak of Ralstonia mannitolilytica bloodstream infections in Germany from March to September 2026 included 16 cases (≤ 6 allelic differences using core genome multilocus sequence typing) across seven hospitals. Epidemiological investigations supported by a large language model, identified prefilled saline flush syringes of one manufacturer as common exposure across all cases. The manufacturer initiated a temporary quarantine and suspension of use of this product. Because it was distributed to other countries, cases may have occurred elsewhere, prompting this report.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.",
    "Postgraduate Training for Applied Epidemiology (PAE), Department for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.",
    "European Programme for Intervention Epidemiology Training (EPIET), European Centre for Disease Prevention and Control, Stockholm, Sweden.",
    "Federal Institute for Drugs and Medical Devices (BfArM), Bonn, Germany.",
    "Genome Competence Centre (MF 1), Robert Koch Institute, Berlin, Germany.",
    "Centre for Biological Threats and Special Pathogens (ZBS 2), Robert Koch Institute, Berlin, Germany.",
    "Institute for Infection Control and Prevention, Medical Center - University of Freiburg, Freiburg, Germany.",
    "Pharmacy, Medical Center - University of Freiburg, Freiburg, Germany.",
    "National Reference Centre for Surveillance of Nosocomial Infections, Berlin, Germany.",
    "Institute of Hygiene and Environmental Medicine, Charité - Universitätsmedizin Berlin, Berlin, Germany.",
    "Pharmacy, Charité-Universitätsmedizin Berlin, Berlin, Germany.",
    "Institute for Hygiene, University Hospital Münster, Münster, Germany.",
    "Health Authority Düsseldorf, Düsseldorf, Germany.",
    "Department of Health Protection, Infection control and Epidemiology State Health Office, Ministry of Social Affairs, Labour and Health Baden-Wuerttemberg, Stuttgart, Germany.",
    "Health Authority Berlin-Mitte, Berlin, Germany.",
    "Infection Prevention and Control Unit, University Hospital Düsseldorf, Düsseldorf, Germany.",
    "Institute of Hygiene, Hospital Epidemiology and Environmental Health, University of Leipzig Medical Center, Leipzig, Germany.",
    "Städtisches Klinikum Görlitz, Görlitz, Germany.",
    "Städtisches Klinikum Karlsruhe, Karlsruhe, Germany.",
    "National Reference Centre for Bacteriology, Inciensa, Tres Ríos, Costa Rica.",
    "Health Authority Charlottenburg-Wilmersdorf, Berlin, Germany.",
    "Institute for Medical Microbiology and Infection Control, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt am Main, Germany.",
    "German National Consiliary Laboratory on Cystic Fibrosis Bacteriology, Frankfurt am Main, Germany."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 32,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Sofia Burdi"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Lukas Herrmann"
    },
    {
      "affs": [
        3
      ],
      "name": "Sophia N Koerdt"
    },
    {
      "affs": [
        4
      ],
      "name": "Silver A Wolf"
    },
    {
      "affs": [
        5
      ],
      "name": "Sandra Appelt"
    },
    {
      "affs": [
        0
      ],
      "name": "Mirco Sandfort"
    },
    {
      "affs": [
        6
      ],
      "name": "Barbara Maier"
    },
    {
      "affs": [
        6
      ],
      "name": "Sandra Reuter"
    },
    {
      "affs": [
        7
      ],
      "name": "Martin J Hug"
    },
    {
      "affs": [
        8,
        9
      ],
      "name": "Nicholas Jakob Böhm"
    },
    {
      "affs": [
        8,
        9
      ],
      "name": "Gizem Karadag"
    },
    {
      "affs": [
        10
      ],
      "name": "Georg Berndt"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Achim Dörre"
    },
    {
      "affs": [
        11
      ],
      "name": "Vera Schwierzeck"
    },
    {
      "affs": [
        11
      ],
      "name": "Linda Behrends"
    },
    {
      "affs": [
        12
      ],
      "name": "Pascal Kreuzer"
    },
    {
      "affs": [
        13
      ],
      "name": "Julia Kuhn"
    },
    {
      "affs": [
        14
      ],
      "name": "Lukas Murajda"
    },
    {
      "affs": [
        15
      ],
      "name": "Saskia Roßbach"
    },
    {
      "affs": [
        16
      ],
      "name": "Susanne Kolbe-Busch"
    },
    {
      "affs": [
        17
      ],
      "name": "Cornelia Seidel"
    },
    {
      "affs": [
        18
      ],
      "name": "Patrick Jung"
    },
    {
      "affs": [
        19
      ],
      "name": "Grettel Chanto Chacón"
    },
    {
      "affs": [
        20
      ],
      "name": "Irina Zuschneid"
    },
    {
      "affs": [
        4
      ],
      "name": "Somayyeh Sedaghatjoo"
    },
    {
      "affs": [
        4
      ],
      "name": "Maximilian Driller Povill"
    },
    {
      "affs": [
        5
      ],
      "name": "Holger C Scholz"
    },
    {
      "affs": [
        11
      ],
      "name": "Alexander Mellmann"
    },
    {
      "affs": [
        0
      ],
      "name": "Tim Eckmanns"
    },
    {
      "affs": [
        3
      ],
      "name": "Josef Zündorf"
    },
    {
      "affs": [
        21,
        22
      ],
      "name": "Michael Hogardt"
    },
    {
      "affs": [
        0
      ],
      "name": "Sebastian Haller"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/b1xe2ye38nvvp.bib",
  "cited_by": 0,
  "doi": "10.2807/1560-7917.es.2026.31.40.2600819",
  "fulltext_url": "https://europepmc.org/articles/PMC13653210",
  "id": "b1xe2ye38nvvp",
  "issns": [
    "1025-496X",
    "1560-7917"
  ],
  "landing_url": "https://europepmc.org/article/MED/42852523",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2725|Infection Control in Healthcare"
    ]
  ],
  "openalex": "W7221188148",
  "pdf_url": "https://europepmc.org/articles/PMC13653210?pdf=render",
  "pmcid": "PMC13653210",
  "pmid": "42852523",
  "published": "2026-10-01",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/b1xe2ye38nvvp.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:18:10Z",
      "native_id": "MED:42852523",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42852523"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2725|Infection Control in Healthcare",
      "subfield": "infectious-disease"
    }
  ],
  "title": "Nosocomial outbreak of Ralstonia mannitolilytica associated with prefilled saline flush syringes distributed in Europe, Germany, March to September 2026.",
  "title_text": "Nosocomial outbreak of Ralstonia mannitolilytica associated with prefilled saline flush syringes distributed in Europe, Germany, March to September 2026.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:18:10Z",
  "url": "https://research.draconitic.com/paper/b1xe2ye38nvvp",
  "venue": "Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin",
  "versions": []
}