{
  "abstract": "Background/Objectives: Postintubation hypotension (PIH) is an important complication of emergency endotracheal intubation in trauma patients. However, the applicability of preintubation predictors of PIH in trauma patients undergoing emergency endotracheal intubation in the emergency department (ED) remains uncertain. Here, we aimed to develop and internally validate a preintubation prediction model for PIH in such patients. Methods: This retrospective cohort included trauma patients aged ≥ 15 years undergoing emergency endotracheal intubation in the ED during 2015–2023. PIH was defined as systolic blood pressure < 90 mmHg within 30 min after intubation. Eight preintubation candidate predictors were evaluated using logistic regression with backward elimination. Internal validation used 2000 bootstrap resamples repeating the entire variable-selection procedure. Results: Among 348 patients, 60 (17.2%) developed PIH; 345 patients with 57 PIH events had complete data for model development. The final model retained systolic blood pressure, body temperature, hematocrit, and torso injury, with adjusted odds ratios of 1.19 per 10-mmHg lower systolic blood pressure, 1.48 per 1 °C lower temperature, 1.33 per 5-percentage-point lower hematocrit, and 3.26 for torso injury. The apparent and optimism-corrected areas under the receiver operating characteristic curve were 0.742 and 0.700, respectively. Conclusions: A four-variable preintubation prediction model demonstrated modest optimism-corrected discrimination and substantial model-selection uncertainty. External validation and assessment of clinical utility are required before clinical implementation.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Anesthesiology, Faculty of Medicine, Prince of Songkla University, Hat Yai 90110, Thailand",
    "Division of Trauma and Critical Care, Department of Surgery, Faculty of Medicine, Prince of Songkla University, Hat Yai 90110, Thailand",
    "Department of Emergency Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai 90110, Thailand"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Chanatthee Kitsiripant",
      "orcid": "0000-0003-1504-9336"
    },
    {
      "affs": [
        1
      ],
      "name": "Komet Thongkhao"
    },
    {
      "affs": [
        1
      ],
      "name": "Osaree Akaraborworn"
    },
    {
      "affs": [
        2
      ],
      "name": "Siriwimon Tantarattanapong"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/b4wkx8r92n8cf.bib",
  "cited_by": 0,
  "doi": "10.3390/jcm15208102",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13706554/?tool=EBI",
  "id": "b4wkx8r92n8cf",
  "issns": [
    "2077-0383"
  ],
  "landing_url": "https://www.mdpi.com/2077-0383/15/20/8102",
  "language": "eng",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2703|Airway Management and Intubation Techniques"
    ]
  ],
  "openalex": "W7222979831",
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13706554/pdf/?tool=EBI",
  "pmcid": "PMC13706554",
  "pmid": null,
  "published": "2026-10-01",
  "publisher": "MDPI AG",
  "ris": "https://research.draconitic.com/paper/b4wkx8r92n8cf.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:20:01Z",
      "native_id": "10.3390/jcm15208102",
      "source": "crossref",
      "url": "https://www.mdpi.com/2077-0383/15/20/8102"
    },
    {
      "first_seen": "2026-10-30T12:21:45Z",
      "native_id": "PMC:PMC13706554",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13706554"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2703|Airway Management and Intubation Techniques",
      "subfield": "surgery"
    }
  ],
  "title": "Development and Internal Validation of a Preintubation Prediction Model for Postintubation Hypotension in Trauma Patients Undergoing Emergency Endotracheal Intubation: A Retrospective Cohort Study",
  "title_text": "Development and Internal Validation of a Preintubation Prediction Model for Postintubation Hypotension in Trauma Patients Undergoing Emergency Endotracheal Intubation: A Retrospective Cohort Study",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:21:45Z",
  "url": "https://research.draconitic.com/paper/b4wkx8r92n8cf",
  "venue": "Journal of Clinical Medicine",
  "versions": []
}