{
  "abstract": "The remediation of benzodiazepine residues from industrial discharge remains a critical environmental challenge due to their chemical stability and neurotoxic potential. In this study, cellulose sludge from the pulp-and-paper industry was successfully upcycled into Ca2+-cross-linked sodium alginate hydrogel beads for the targeted removal of bromazepam (BZP). This work represents the first systematic investigation into BZP sequestration using a waste-derived hybrid hydrogel, at deliberately low concentrations (0.5–5.4 mg L–1), kept as close to environmentally relevant levels as the analytical method allows and within the range reported for point-source pharmaceutical effluents. The beads exhibited a rough filamentous surface and an interconnected 3D porous network characterized by a mesoporous texture (SSA: 9.35 m2 g–1; pore volume: 0.04 cm3 g–1) and an amphoteric surface (pHPZC = 8.04). Kinetic studies revealed a rapid initial uptake reaching an experimental capacity of 0.25 mg g–1 at 180 min, with the Elovich model providing the best statistical fit (R2 = 0.994; AIC = −56.9; BIC = −56.7), consistent with adsorption on energetically heterogeneous sites governed by coverage-dependent rate decay. Because the isotherms were measured in this dilute range, no saturation plateau was reached: the equilibrium data were best described by the Freundlich model at 25 °C and by a linear (Henry-type) model at 35 and 45 °C. The hydrogel beads were efficiently regenerated using 0.1 M HCl, maintaining structural integrity and performance across four consecutive cycles (BZP removal of approximately 13–15% in each cycle, with no systematic decline). This study provides a sustainable, zero-waste strategy for the valorization of abundant industrial residues into functional bioadsorbents, directly supporting circular economy goals for emerging contaminant mitigation.",
  "abstract_shown": true,
  "affiliations": [
    "Federal University of Fronteira Sul , , , ,",
    "Federal University of Santa Catarina , , ,"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 11,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Danieli Brandler"
    },
    {
      "affs": [
        0
      ],
      "name": "Bruna da Conceição Marques"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Gabriel Tochetto",
      "orcid": "0000-0003-1656-505X"
    },
    {
      "affs": [
        0
      ],
      "name": "Yago Colares Pinto"
    },
    {
      "affs": [
        0
      ],
      "name": "William Kubiaki Levandoski"
    },
    {
      "affs": [
        0
      ],
      "name": "Aluizio Araújo Passos"
    },
    {
      "affs": [
        0
      ],
      "name": "Gabriela Perusin Flores"
    },
    {
      "affs": [
        0
      ],
      "name": "Vitória Bôaventura Midon"
    },
    {
      "affs": [
        0
      ],
      "name": "Arielle Fornari"
    },
    {
      "affs": [
        0
      ],
      "name": "Eduardo Pavan Korf"
    },
    {
      "affs": [
        0
      ],
      "name": "Gean Delise Leal Pasquali"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/b5j1s8qjkpw1t.bib",
  "cited_by": 0,
  "doi": "10.1021/acsomega.6c09601",
  "fulltext_url": null,
  "id": "b5j1s8qjkpw1t",
  "issns": [
    "2470-1343"
  ],
  "landing_url": "https://pubs.acs.org/acsodf/article/doi/10.1021/acsomega.6c09601/5463393/Valorization-of-Cellulose-Sludge-as-a-Sodium",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [],
  "openalex": null,
  "pdf_url": "https://pubs.acs.org/doi/pdf/10.1021/acsomega.6c09601",
  "pmcid": null,
  "pmid": null,
  "published": "2026-11-04",
  "publisher": "American Chemical Society (ACS)",
  "ris": "https://research.draconitic.com/paper/b5j1s8qjkpw1t.ris",
  "sources": [
    {
      "first_seen": "2026-11-04T12:21:04Z",
      "native_id": "10.1021/acsomega.6c09601",
      "source": "crossref",
      "url": "https://pubs.acs.org/acsodf/article/doi/10.1021/acsomega.6c09601/5463393/Valorization-of-Cellulose-Sludge-as-a-Sodium"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "issn:2470-1343",
      "subfield": "general"
    }
  ],
  "title": "Valorization of Cellulose Sludge as a Sodium Alginate-Based Bioadsorbent for Bromazepam Removal from Water",
  "title_text": "Valorization of Cellulose Sludge as a Sodium Alginate-Based Bioadsorbent for Bromazepam Removal from Water",
  "type": "peer-reviewed",
  "updated_at": "2026-11-06T00:21:08Z",
  "url": "https://research.draconitic.com/paper/b5j1s8qjkpw1t",
  "venue": "ACS Omega",
  "versions": []
}