{
  "abstract": "Retroperitoneal sarcomas are rare, aggressive malignancies that often present late owing to the retroperitoneum's anatomical expansibility. Dedifferentiated liposarcoma is the most common high-grade subtype. We describe the technical management of a 65-year-old man with a giant retroperitoneal dedifferentiated liposarcoma involving multiple adjacent organs, treated by radical en bloc multivisceral resection including the kidney, adrenal gland, spleen, and distal pancreas. Postoperative recovery was complicated by a Grade B pancreatic leak and a left pleural effusion, managed with percutaneous and thoracic drainage, respectively. Histology confirmed a dedifferentiated liposarcoma resected with clear (R0) margins. At 18 months, no radiological recurrence had been observed, although this follow-up interval remains short relative to the recurrence interval reported for high-grade dedifferentiated liposarcoma. This case illustrates the technical conduct of multivisceral resection for a giant retroperitoneal sarcoma and the perioperative surveillance required to manage expected complications such as pancreatic leak.",
  "abstract_shown": true,
  "affiliations": [
    "Department of General Surgery, The Dudley Group NHS Foundation Trust, Pensnett Road, Dudley, West Midlands, DY1 2HQ, United Kingdom.",
    "College of Health and Life Science, Aston Medical School, School of Medicine, Pharmacy and Biosciences, Aston University, Birmingham B4 7ET, UK, United Kingdom.",
    "Department of Gastrointestinal Surgery AST Ascoli Piceno, Madonna del Soccorso Hospital, San Benedetto del Tronto, Italy."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Sadik Al-Hassani"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Akinfemi Akingboye",
      "orcid": "0000-0002-0325-8440"
    },
    {
      "affs": [
        2
      ],
      "name": "Ilenia Merlini"
    },
    {
      "affs": [
        2
      ],
      "name": "Salomone Di Saverio"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/b5q8mne17j4w2.bib",
  "cited_by": 0,
  "doi": "10.1093/jscr/rjag982",
  "fulltext_url": "https://europepmc.org/articles/PMC13711087",
  "id": "b5q8mne17j4w2",
  "issns": [
    "2042-8812"
  ],
  "landing_url": "https://europepmc.org/article/MED/42948301",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "AcademicSubjects/MED00910"
    ],
    [
      "heading",
      "Surgical Technique"
    ],
    [
      "heading",
      "jscrep/0160"
    ],
    [
      "openalex",
      "2740|Sarcoma Diagnosis and Treatment"
    ]
  ],
  "openalex": "W7223860132",
  "pdf_url": "https://europepmc.org/articles/PMC13711087?pdf=render",
  "pmcid": "PMC13711087",
  "pmid": "42948301",
  "published": "2026-10-27",
  "publisher": "Oxford University Press",
  "ris": "https://research.draconitic.com/paper/b5q8mne17j4w2.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T00:20:33Z",
      "native_id": "MED:42948301",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42948301"
    },
    {
      "first_seen": "2026-10-31T12:21:55Z",
      "native_id": "PMC13711087",
      "source": "pmc",
      "url": "https://doi.org/10.1093/jscr/rjag982"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "journal-openalex:2746|Gastrointestinal disorders and treatments",
      "subfield": "surgery"
    }
  ],
  "title": "En bloc multivisceral resection for a giant retroperitoneal dedifferentiated liposarcoma: technical considerations.",
  "title_text": "En bloc multivisceral resection for a giant retroperitoneal dedifferentiated liposarcoma: technical considerations.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-31T12:21:55Z",
  "url": "https://research.draconitic.com/paper/b5q8mne17j4w2",
  "venue": "Journal of surgical case reports",
  "versions": []
}