{
  "abstract": "This study focused on Eranthis sibirica and E. tanhoensis (Ranunculaceae), endemic species of Southeastern Siberia. Until recently, these plants had not been sufficiently studied from a phytochemical perspective. The aim of this work was to analyze the phenolic composition and antioxidant properties of 70% ethanolic extracts of their leaves. Liquid chromatography coupled with high-resolution mass spectrometry (LC-HRMS) was used to analyze metabolites in Eranthis sibirica and E. tanhoensis extracts. The free-radical-scavenging ability of the extracts was assessed using the DPPH method. LC–HRMS metabolomic profiling of the leaf extracts from E. sibirica and E. tanhoensis revealed a diverse range of phenolic constituents; among them, 25 compounds were annotated for the first time for this genus, while the remaining 19 had been previously reported. These included flavonols (16 components), flavanones (8), flavones and isoflavones (5), chalcones (5), flavans (1), catechins (1), and phenolic acids and their derivatives (8). The E. tanhoensis leaf extracts were found to have higher phenolic content (total phenolic content of 3.07 g per 100 g dry weight) and greater DPPH radical scavenging activity (IC50 = 268.45 μg/mL dry weight) than E. sibirica. These findings indicate that the species with the higher phenolic accumulation also displays stronger antioxidant activity, suggesting that both species—particularly E. tanhoensis—warrant further phytochemical and biological investigation.",
  "abstract_shown": true,
  "affiliations": [
    "Central Siberian Botanical Garden, Siberian Branch of Russian Academy of Sciences (SB RAS), Novosibirsk 630090, Russia",
    "Komarov Botanical Institute of Russian Academy of Sciences, St. Petersburg 197022, Russia",
    "Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences (SB RAS), Novosibirsk 630090, Russia",
    "Department of Natural Sciences, Novosibirsk State University, Novosibirsk 630090, Russia",
    "Faculty of Chemistry, National Research Tomsk State University, Tomsk 634028, Russia",
    "Laboratory of the Herbarium, Tomsk State University, Tomsk 634050, Russia",
    "State Key Laboratory of Plant Diversity and Specialty Crops, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 11,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Vera A. Kostikova",
      "orcid": "0000-0002-5213-2166"
    },
    {
      "affs": [
        1
      ],
      "name": "Natalia V. Petrova",
      "orcid": "0000-0003-4455-6572"
    },
    {
      "affs": [
        2
      ],
      "name": "Alexander A. Chernonosov",
      "orcid": "0000-0001-8362-2443"
    },
    {
      "affs": [
        2,
        3
      ],
      "name": "Vladimir V. Koval",
      "orcid": "0000-0002-2577-2184"
    },
    {
      "affs": [
        4
      ],
      "name": "Maria V. Lyapunova",
      "orcid": "0000-0003-1885-8657"
    },
    {
      "affs": [
        4
      ],
      "name": "Yulia D. Razgulyaeva",
      "orcid": "0000-0002-3172-4197"
    },
    {
      "affs": [
        3
      ],
      "name": "Evgeniia R. Lazareva",
      "orcid": "0009-0003-7842-847X"
    },
    {
      "affs": [
        5
      ],
      "name": "Alexander A. Kuznetsov"
    },
    {
      "affs": [
        6
      ],
      "name": "Kun-Li Xiang"
    },
    {
      "affs": [
        6
      ],
      "name": "Wei Wang",
      "orcid": "0000-0001-6901-6375"
    },
    {
      "affs": [
        0
      ],
      "name": "Andrey S. Erst",
      "orcid": "0000-0002-4844-0254"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/b5ty2r6p1g442.bib",
  "cited_by": 0,
  "doi": "10.3390/ijms27219973",
  "fulltext_url": null,
  "id": "b5ty2r6p1g442",
  "issns": [
    "1422-0067"
  ],
  "landing_url": "https://www.mdpi.com/1422-0067/27/21/9973",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [],
  "openalex": null,
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-11-06",
  "publisher": "MDPI AG",
  "ris": "https://research.draconitic.com/paper/b5ty2r6p1g442.ris",
  "sources": [
    {
      "first_seen": "2026-11-10T00:21:27Z",
      "native_id": "10.3390/ijms27219973",
      "source": "crossref",
      "url": "https://www.mdpi.com/1422-0067/27/21/9973"
    }
  ],
  "subjects": [
    {
      "field": "biochemistry",
      "origin": "issn:1422-0067",
      "subfield": "general"
    }
  ],
  "title": "Phenolic Profiles and DPPH Radical-Scavenging Activity of Two Eranthis Species from Southeastern Siberia",
  "title_text": "Phenolic Profiles and DPPH Radical-Scavenging Activity of Two Eranthis Species from Southeastern Siberia",
  "type": "peer-reviewed",
  "updated_at": "2026-11-10T00:21:27Z",
  "url": "https://research.draconitic.com/paper/b5ty2r6p1g442",
  "venue": "International Journal of Molecular Sciences",
  "versions": []
}