{
  "abstract": "Enantioselective catalysis transforming alkenes to chiral molecules have been a breakthrough in the field of organic synthesis. Though a major challenge persists. The “privileged” chiral catalyst capacities depend on the geometry of the olefin substrate which can be either E or Z. Enantioselective catalysis allowing to convert both alkene stereoisomers to a single chiral molecule promises sustainable synthetic routes and novel mechanistic strategies towards chiral molecule synthesis. Enantioselective methods towards the functionalization of E/Z-alkenes, which has largely taken advantages of the recent development of earth-abundant 3d metal catalysis, are covered in this revue. An emphasis on the mechanisms accounting for the observed stereoconvergence and enantioselectivity is proposed.",
  "abstract_shown": true,
  "affiliations": [
    "Institut des Sciences Chimiques de Rennes (ISCR, UMR 6226), Univ. Rennes, CNRS, 263 Avenue du Général Leclerc, Rennes Cedex, 35042",
    "Process Chemistry R&D, Idorsia Pharmaceuticals Ltd., Hegenheimermattweg 91, Allschwil, Switzerland, CH-4123"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Guillaume Delestras"
    },
    {
      "affs": [
        1
      ],
      "name": "John Henry Reed"
    },
    {
      "affs": [
        0
      ],
      "name": "Coralie Duchemin",
      "orcid": "0000-0001-7531-3755"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/b69nraj01zh1p.bib",
  "cited_by": 0,
  "doi": "10.26434/chemrxiv.15010148/v1",
  "fulltext_url": null,
  "id": "b69nraj01zh1p",
  "issns": [],
  "landing_url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15010148/v1",
  "language": null,
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1605|Asymmetric Synthesis and Catalysis"
    ]
  ],
  "openalex": "W7221136769",
  "pdf_url": "https://chemrxiv.org/doi/pdf/10.26434/chemrxiv.15010148/v1",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-09",
  "publisher": "American Chemical Society (ACS)",
  "ris": "https://research.draconitic.com/paper/b69nraj01zh1p.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:22Z",
      "native_id": "10.26434/chemrxiv.15010148",
      "source": "chemrxiv",
      "url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15010148/v1"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1605|Asymmetric Synthesis and Catalysis",
      "subfield": "organic"
    }
  ],
  "title": "Earth-abundant 3d metal-catalyzed enantioselective catalysis towards the functionalization of E/Zalkenes mixtures.",
  "title_text": "Earth-abundant 3d metal-catalyzed enantioselective catalysis towards the functionalization of E/Zalkenes mixtures.",
  "type": "preprint",
  "updated_at": "2026-10-30T12:17:22Z",
  "url": "https://research.draconitic.com/paper/b69nraj01zh1p",
  "venue": "ChemRxiv",
  "versions": []
}