{
  "abstract": "Background\n\nObesity/adiposity-based chronic disease is a chronic progressive relapsing disease linked to several comorbidities, with rising prevalence in Egypt. Limited local guidelines and healthcare challenges necessitate evidence-based, culturally adapted strategies.Methods\n\nThe Egyptian Medical Association for the Study of Obesity convened a clinical multidisciplinary panel to develop consensus recommendations. Evidence was synthesized from literature, prioritizing resource-limited settings and special situations.Result\n\nAssessment: Move beyond Body Mass Index to include waist circumference, waist/height ratio, body composition, and screening for obesity-related complications and diseases. Lifestyle Interventions: a-Nutrition: Mediterranean/dietary approach to stop hypertension diets, slow eating, and supervised fasting (eg Ramadan and Christian). b-Activity: Culturally tailored approaches (eg prayer-time movement and Arabic apps). c-Behavior: Cognitive-behavioral therapy and family-inclusive support. Pharmacotherapy: Use of approved agents (orlistat, naltrexone/bupropion, liraglutide, semaglutide, and tirzepatide) according to obesity-related complications and diseases and age group. Avoid GLP-1, GLP-1/GIP analogues in patients with medullary thyroid cancer, and all agents during pregnancy. Bariatric Surgery: Indicated for body mass index ≥40 kg/m² (or ≥35 with obesity-related complications and diseases), with lifelong micronutrient supplementation. Special Populations: a-Adolescents: Focus on growth, not only weight-loss; consider pharmacotherapy in different age groups. b-Elderly: Prioritize muscle preservation; avoid weight loss unless obesity-related complications and diseases exist. c-Pregnancy: No weight loss; delay postpartum interventions until lactation is established. Policy Actions: Mandate food labeling, tax sugar-sweetened beverages, and integrate obesity services into primary healthcare.Conclusion\n\nThese recommendations provide a pragmatic framework for obesity/adiposity-based chronic disease management in Egypt, emphasizing affordable, patient-centered care, and clinical multidisciplinary collaboration and policy support.",
  "abstract_shown": true,
  "affiliations": [
    "Hepatology and Gastroenterology Division, Faculty of Medicine, Cairo University, Cairo, Egypt.",
    "Department of Anaesthesia & SICU and Pain Management Kasr Alainy School of Medicine, Cairo University Cairo Egypt.",
    "School of Medicine, Cairo University, Cairo, Egypt.",
    "Department of Anesthesiology, SICU and Pain, Kasr Alainy School of Medicine, Cairo University, Cairo, Egypt.",
    "Family Medicine Department Kasr Alainy School of Medicine, Cairo University, Cairo, Egypt.",
    "Clinical Nutrition Department Shifa Hospitals Group Cairo Egypt.",
    "Public Health and Nutrition High Institute of Public Health, Alexandria, Egypt.",
    "Department of Anesthesiology Kasr Alainy School of Medicine, Cairo University, Cairo, Egypt.",
    "Department of General Surgery Kasr Alainy School of Medicine, Cairo University, Cairo, Egypt.",
    "Department of Internal Medicine & Nephrology Cairo University, Cairo, Egypt.",
    "Department of Pediatric Diabetes and Endocrinology Kasr Alainy Faculty of Medicine, Cairo University, Cairo, Egypt.",
    "Department of Internal Medicine, Diabetes and Endocrinology Kasr Alainy Faculty of Medicine, Cairo University, Cairo, Egypt.",
    "Department of Psychiatry Kasr Alainy Faculty of Medicine, Cairo University, Cairo, Egypt.",
    "Department of Cardiology Faculty of Medicine, Cairo University, Cairo, Egypt.",
    "Department of Internal Medicine and Diabetes Kasr Alainy Faculty of Medicine, Cairo University, Cairo, Egypt.",
    "Internal Medicine, Diabetes Mellitus, and Endocrinology Division Kasr Alainy School of Medicine, Cairo University, Cairo, Egypt."
  ],
  "article_type": "article commentary",
  "arxiv": null,
  "author_total": 16,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Mona A Hegazy",
      "orcid": "0009-0009-2030-0856"
    },
    {
      "affs": [
        1
      ],
      "name": "Amr Mattar"
    },
    {
      "affs": [
        2
      ],
      "name": "Maissa Mohamed Shawky"
    },
    {
      "affs": [
        3
      ],
      "name": "Dina Soliman"
    },
    {
      "affs": [
        4
      ],
      "name": "Maha Mowafy"
    },
    {
      "affs": [
        5
      ],
      "name": "Yasmine Mohamed NourEldin"
    },
    {
      "affs": [
        6
      ],
      "name": "Ahmed Madbouli Noweir"
    },
    {
      "affs": [
        7
      ],
      "name": "Mohamed Kamal Aboulghate"
    },
    {
      "affs": [
        8
      ],
      "name": "Mostafa Elshazli"
    },
    {
      "affs": [
        9
      ],
      "name": "May AbdelMoneim Hassaballa"
    },
    {
      "affs": [
        10
      ],
      "name": "Shereen Abdelghaffar",
      "orcid": "0000-0002-2876-4809"
    },
    {
      "affs": [
        11
      ],
      "name": "Heba Morad Bahgat"
    },
    {
      "affs": [
        12
      ],
      "name": "Noha Sabry"
    },
    {
      "affs": [
        13
      ],
      "name": "Hesham Salah Eldin Taha",
      "orcid": "0000-0002-6558-8170"
    },
    {
      "affs": [
        14
      ],
      "name": "Inass Shaltout"
    },
    {
      "affs": [
        15
      ],
      "name": "Mona Yousry"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/b6xvwk9wmk7xk.bib",
  "cited_by": 0,
  "doi": "10.2147/dmso.s629991",
  "fulltext_url": "https://europepmc.org/articles/PMC13726600",
  "id": "b6xvwk9wmk7xk",
  "issns": [
    "1178-7007"
  ],
  "landing_url": "https://europepmc.org/article/MED/42974480",
  "language": "eng",
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Expert Opinion"
    ],
    [
      "openalex",
      "2736|Pharmacology and Obesity Treatment"
    ]
  ],
  "openalex": "W7224136908",
  "pdf_url": "https://europepmc.org/articles/PMC13726600?pdf=render",
  "pmcid": "PMC13726600",
  "pmid": "42974480",
  "published": "2026-10-29",
  "publisher": "Dove Press",
  "ris": "https://research.draconitic.com/paper/b6xvwk9wmk7xk.ris",
  "sources": [
    {
      "first_seen": "2026-11-04T15:20:47Z",
      "native_id": "MED:42974480",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42974480"
    },
    {
      "first_seen": "2026-11-05T12:22:54Z",
      "native_id": "PMC13726600",
      "source": "pmc",
      "url": "https://doi.org/10.2147/dmso.s629991"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2736|Pharmacology and Obesity Treatment",
      "subfield": "pharmacology-toxicology"
    }
  ],
  "title": "Management of Obesity in Special Populations and Limited-Resource Settings: An Egyptian Medical Position Statement.",
  "title_text": "Management of Obesity in Special Populations and Limited-Resource Settings: An Egyptian Medical Position Statement.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-06T12:22:30Z",
  "url": "https://research.draconitic.com/paper/b6xvwk9wmk7xk",
  "venue": "Diabetes, metabolic syndrome and obesity : targets and therapy",
  "versions": []
}