{
  "abstract": "The integrity of evidence synthesis is threatened by problematic randomised controlled trials, where there are serious concerns about the trustworthiness of the data or findings. Such concerns could be due to research misconduct, including fraud, or due to honest critical errors. If these trials are not detected, they may be inadvertently included in systematic reviews and guidelines, potentially distorting their results. To resolve this problem, the INSPECT-SR (Investigating Problematic Clinical Trials in Systematic Reviews) tool has been developed to assess the trustworthiness of randomised controlled trials. This tool will help researchers to identify and exclude problematic trials from systematic reviews. This article describes the development of INSPECT-SR and presents the tool and an associated guidance document.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 54,
  "authors": [
    {
      "name": "Jack Wilkinson"
    },
    {
      "name": "Lisa Bero"
    },
    {
      "name": "Calvin Heal"
    },
    {
      "name": "Ella Flemyng"
    },
    {
      "name": "Georgios Antoniou"
    },
    {
      "name": "Tony Aburrow"
    },
    {
      "name": "Zarko Alfirevic"
    },
    {
      "name": "Alison Avenell"
    },
    {
      "name": "Virginia Barbour"
    },
    {
      "name": "Vincenzo Berghella"
    },
    {
      "name": "Dorothy Bishop"
    },
    {
      "name": "Esmée Bordewijk"
    },
    {
      "name": "Nicholas Brown"
    },
    {
      "name": "Jana Christopher"
    },
    {
      "name": "Mike Clarke"
    },
    {
      "name": "Darren Dahly"
    },
    {
      "name": "Jane Dennis"
    },
    {
      "name": "Patrick Dicker"
    },
    {
      "name": "Jo Dumville"
    },
    {
      "name": "Helen Frankish"
    },
    {
      "name": "Andrew Grey"
    },
    {
      "name": "Steph Grohmann"
    },
    {
      "name": "Lyle Gurrin"
    },
    {
      "name": "Jill Hayden"
    },
    {
      "name": "James Heathers"
    },
    {
      "name": "Kylie Hunter"
    },
    {
      "name": "Ian Hussey"
    },
    {
      "name": "Lukas Jung"
    },
    {
      "name": "Emily Lam"
    },
    {
      "name": "Toby Lasserson"
    },
    {
      "name": "Sarah Lensen"
    },
    {
      "name": "Tianjing Li"
    },
    {
      "name": "Wentao Li"
    },
    {
      "name": "Jianping Liu"
    },
    {
      "name": "Elizabeth Loder"
    },
    {
      "name": "Andreas Lundh"
    },
    {
      "name": "Gideon Meyerowitz-Katz"
    },
    {
      "name": "Ben Mol"
    },
    {
      "name": "Florian Naudet"
    },
    {
      "name": "Anna Noel-Storr"
    },
    {
      "name": "Neil O'Connell"
    },
    {
      "name": "Lisa Parker"
    },
    {
      "name": "Rita Redberg"
    },
    {
      "name": "Barbara Redman"
    },
    {
      "name": "Rachel Richardson"
    },
    {
      "name": "Anna Lene Seidler"
    },
    {
      "name": "Kyle Sheldrick"
    },
    {
      "name": "Emma Sydenham"
    },
    {
      "name": "Madelon van Wely"
    },
    {
      "name": "Colby Vorland"
    },
    {
      "name": "Rui Wang"
    },
    {
      "name": "Stephanie Weibel"
    },
    {
      "name": "Matthias Wjst"
    },
    {
      "name": "Jamie Kirkham"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/bae6vsff4h0sz.bib",
  "cited_by": 4,
  "doi": "10.1136/bmj-2026-100611",
  "fulltext_url": null,
  "id": "bae6vsff4h0sz",
  "issns": [
    "1756-1833"
  ],
  "landing_url": "https://univ-rennes.hal.science/hal-05796768v1",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.sdv"
    ],
    [
      "openalex",
      "1804|Meta-analysis and systematic reviews"
    ]
  ],
  "openalex": "W7214235388",
  "pdf_url": "https://www.bmj.com/content/bmj/394/bmj-2026-100611.full.pdf",
  "pmcid": null,
  "pmid": "42785807",
  "published": "2026-09-24",
  "publisher": "BMJ",
  "ris": "https://research.draconitic.com/paper/bae6vsff4h0sz.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:55Z",
      "native_id": "hal-05796768",
      "source": "hal",
      "url": "https://univ-rennes.hal.science/hal-05796768v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "hal:0.sdv",
      "subfield": "general"
    }
  ],
  "title": "INSPECT-SR tool for assessing trustworthiness of randomised controlled trials",
  "title_text": "INSPECT-SR tool for assessing trustworthiness of randomised controlled trials",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:55Z",
  "url": "https://research.draconitic.com/paper/bae6vsff4h0sz",
  "venue": "BMJ - British Medical Journal",
  "versions": []
}