{
  "abstract": "Purpose\n\nTo determine the effect of mindfulness-based cognitive therapy on kinesiophobia in older adults with chronic knee osteoarthritis.Patients and methods\n\nThis randomized clinical trial conducted among 56 older patients with knee osteoarthritis at health centers in Kashan, Iran, in 2024. Participants were selected via consecutive sampling and randomly assigned to either an intervention (n = 28) or a control (n = 28) group using block randomization. The intervention group participated in eight 90 minute sessions of Mindfulness Based Cognitive Therapy, while the control group received routine care. Kinesiophobia was measured with the Tampa Scale for Kinesiophobia (TSK11) at baseline, week 4 (immediately post intervention), and week 8 (four week follow up). Covariate adjusted repeated measures ANCOVA was performed, adjusting for age, number of children, and baseline pain intensity. Statistical significance was set at p < 0.05. All participants completed follow up.Results\n\nThe mean kinesiophobia score decreased from 29.46 ± 3.81 at baseline to 25.68 ± 3.22 at week 8 in the intervention group and from 28.64 ± 4.78 to 26.68 ± 5.15 in the control group. The adjusted repeated-measures analysis showed a significant group-by-time interaction (Wilks' Λ = 0.88, F(2.50) = 3.34, p = 0.040, ηp² = 0.11), indicating different trajectories of change between groups. However, adjusted between-group differences were not statistically significant at baseline, week 4, or week 8 (all p > 0.05). The adjusted difference in change from baseline to week 8 was -1.60 points (95% CI -3.25 to 0.05; p = 0.05). Within-group Bonferroni-adjusted comparisons showed significant reductions across all time intervals in the intervention group (all p < 0.001) and from baseline to week 4 and week 8 in the control group (p = 0.0022 and p = 0.0028, respectively), but not between weeks 4 and 8 (p = 0.13).Conclusion\n\nFour weeks of MBCT may influence the trajectory of kinesiophobia over time in older adults with knee osteoarthritis.Trial registration\n\nRegistered in the Iranian Registry of Clinical Trials (IRCT20231105059961N1).",
  "abstract_shown": true,
  "affiliations": [
    "Trauma Nursing Research Center, Kashan University of Medical Sciences, Kashan, Iran.",
    "Social Determinants of Health (SDH) Research Center, Kashan University of Medical Sciences, Kashan, Iran.",
    "Isfahan University of Medical Sciences, Department of Orthopedics and Joint Surgery, Isfahan, Iran."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Zahra Kheirkhah"
    },
    {
      "affs": [
        0
      ],
      "name": "Fatemeh Fallahi",
      "orcid": "0000-0001-9948-8867"
    },
    {
      "affs": [
        0
      ],
      "name": "Khadijeh Sharifi",
      "orcid": "0000-0002-7531-5440"
    },
    {
      "affs": [
        1
      ],
      "name": "Fatemeh Sadat Asgarian",
      "orcid": "0000-0002-2567-5616"
    },
    {
      "affs": [
        2
      ],
      "name": "Amir Hossein Fallahi"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/batppamr0axb7.bib",
  "cited_by": 0,
  "doi": "10.2147/cia.s638393",
  "fulltext_url": "https://europepmc.org/articles/PMC13695361",
  "id": "batppamr0axb7",
  "issns": [
    "1176-9092",
    "1178-1998"
  ],
  "landing_url": "https://europepmc.org/article/MED/42927343",
  "language": "eng",
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2736|Musculoskeletal pain and rehabilitation"
    ]
  ],
  "openalex": "W7223023220",
  "pdf_url": "https://europepmc.org/articles/PMC13695361?pdf=render",
  "pmcid": "PMC13695361",
  "pmid": "42927343",
  "published": "2026-10-20",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/batppamr0axb7.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:21:18Z",
      "native_id": "MED:42927343",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42927343"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2736|Musculoskeletal pain and rehabilitation",
      "subfield": "pharmacology-toxicology"
    }
  ],
  "title": "The Effect of Mindfulness-Based Cognitive Therapy on Kinesiophobia in Older Adults with Chronic Knee Osteoarthritis: A Randomized Controlled Trial.",
  "title_text": "The Effect of Mindfulness-Based Cognitive Therapy on Kinesiophobia in Older Adults with Chronic Knee Osteoarthritis: A Randomized Controlled Trial.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:21:18Z",
  "url": "https://research.draconitic.com/paper/batppamr0axb7",
  "venue": "Clinical interventions in aging",
  "versions": []
}