{
  "abstract": "Background/aim: Hemodialysis patients face a high burden of cardiovascular diseases, which account for over 40% of mortality in this population. In these patients, approximately two-thirds of cardiovascular deaths are due to arrhythmia. The aim of this study was to determine whether the ultrafiltration rate is associated with morphological and functional parameters of the left heart and arrhythmias. Methods: This work was a cross-sectional observational clinical study, with 75 hemodialysis patients. Patients were divided into two groups based on ultrafiltration rate (UFR): higher-UFR group, ultrafiltration rate ≥ 10 mL/kg/h (n = 37); lower-UFR group, ultrafiltration rate < 10 mL/kg/h (n = 38). All patients were analyzed for myocardial morphological and functional parameters and arrhythmias. Results: Statistically significant higher values were observed for the left atrium diameter (LAD) (47.56 ± 4.82 vs. 44.75 ± 2.33 mm, p = 0.0019), the left atrial volume index (LAVI) (43.28 ± 7.13 vs. 36.43 ± 8.52 mL/m², p = 0.0003), and the left ventricular mass index (LVMI) (138.47 ± 29.32 vs. 116.04 ± 31.64 g/m², p = 0.0021) in the higher-UFR group. UFR was associated with LAD (OR: 3.6000, 95% CI: 1.3780-9.4053, p = 0.0089), LAVI (OR: 4.1067, 95% CI: 1.5478-10.8956, p = 0.0045), and LVMI (OR: 4.7619, 95% CI: 1.6825-13.4774, p = 0.0033). The frequency of ventricular and supraventricular arrhythmias was similar between the analyzed patient groups. Conclusions: Higher UFR was associated with structural changes in the left heart (LAVI, LAD, and LVMI), but not with other echocardiographic parameters or arrhythmias in hemodialysis patients.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Intensive Care, Clinic for Internal Medicine, University Clinical Center Tuzla, 75000 Tuzla, Bosnia and Herzegovina.",
    "Department of Gynecology and Obstetrics, University Clinical Center Ljubljana, 1000 Ljubljana, Slovenia.",
    "Department of Pharmacology, Faculty of Medicine, University of Tuzla, 75000 Tuzla, Bosnia and Herzegovina.",
    "Department of Gastroenterology, Clinic for Internal Medicine, University Clinical Center Tuzla, 75000 Tuzla, Bosnia and Herzegovina.",
    "Erbe Elektromedizin GmbH, 72072 Tuebingen, Germany.",
    "Department of Surgery, University Clinical Center Tuzla, 75000 Tuzla, Bosnia and Herzegovina.",
    "Department of Nephrology and Hemodialysis, Clinic for Internal Medicine, University Clinical Center Tuzla, 75000 Tuzla, Bosnia and Herzegovina.",
    "Department of Surgery, Eurofarm Center Policlinic Tuzla, 75000 Tuzla, Bosnia and Herzegovina."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Ammar Brkić"
    },
    {
      "affs": [
        1,
        2
      ],
      "name": "Kenana Ljuca",
      "orcid": "0009-0004-9478-3284"
    },
    {
      "affs": [
        3
      ],
      "name": "Emir Tulumović"
    },
    {
      "affs": [
        2
      ],
      "name": "Nadina Ljuca",
      "orcid": "0009-0008-0832-3644"
    },
    {
      "affs": [
        4
      ],
      "name": "Nermin Salkić",
      "orcid": "0000-0003-4727-9267"
    },
    {
      "affs": [
        0
      ],
      "name": "Emir Bećirović",
      "orcid": "0000-0002-4134-987X"
    },
    {
      "affs": [
        5
      ],
      "name": "Amir Tursunović",
      "orcid": "0000-0002-4075-3790"
    },
    {
      "affs": [
        6
      ],
      "name": "Minela Bećirović",
      "orcid": "0009-0007-4391-5226"
    },
    {
      "affs": [
        7
      ],
      "name": "Bahrudin Hadžiefendić"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/bb26n5mv83fjt.bib",
  "cited_by": 0,
  "doi": "10.3390/clinpract16100182",
  "fulltext_url": "https://europepmc.org/articles/PMC13703219",
  "id": "bb26n5mv83fjt",
  "issns": [
    "2039-7275",
    "2039-7283"
  ],
  "landing_url": "https://europepmc.org/article/MED/42930368",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2727|Dialysis and Renal Disease Management"
    ]
  ],
  "openalex": "W7214893913",
  "pdf_url": "https://europepmc.org/articles/PMC13703219?pdf=render",
  "pmcid": "PMC13703219",
  "pmid": "42930368",
  "published": "2026-09-30",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/bb26n5mv83fjt.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:22:01Z",
      "native_id": "MED:42930368",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42930368"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2727|Dialysis and Renal Disease Management",
      "subfield": "general"
    }
  ],
  "title": "Association of Ultrafiltration Rate with Structural Remodeling of the Left Heart and Arrhythmias in Hemodialysis Patients: A Cross-Sectional Observational Study.",
  "title_text": "Association of Ultrafiltration Rate with Structural Remodeling of the Left Heart and Arrhythmias in Hemodialysis Patients: A Cross-Sectional Observational Study.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:22:01Z",
  "url": "https://research.draconitic.com/paper/bb26n5mv83fjt",
  "venue": "Clinics and practice",
  "versions": []
}