{
  "abstract": "Titanium dioxide, a traditional physical sunscreen agent, has long faced persistent challenges related to light transmission (manifesting as whitening and an unnatural white cast on the skin), high photocatalytic activity, and cytocompatibility concerns. In this work, a composite sunscreen material, mesoporous silica (MSN)@TiO₂, was designed and synthesized by loading titanium dioxide (TiO₂) onto dendritic mesoporous silica. Leveraging the high transparency of dendritic mesoporous silica, MSN@TiO₂ exhibits 30% higher visible light transmittance than commercially available titanium dioxide. In addition, encapsulation within the silica carrier reduces the photocatalytic activity of MSN@TiO₂ to one-seventh of that of commercially available titanium dioxide. Furthermore, we evaluated the cytocompatibility of MSN@TiO₂. Cell Counting Kit-8 (CCK-8) assay results demonstrate that MSN@TiO₂ has a less pronounced effect on L929 cells proliferation compared with commercial TiO₂, indicating favorable L929 cell-based cytocompatibility. This strategy demonstrates that MSN@TiO₂ combines a natural appearance with low photocatalytic activity, offering distinct advantages over conventional titanium dioxide in composite sunscreen materials.",
  "abstract_shown": true,
  "affiliations": [
    "School of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University, Zhongshan 528458, China",
    "School of Pharmacy GDPU, Guangdong Pharmaceutical University, Guangzhou 510006, China",
    "Guangdong B.C. Biotech Company Limited, Zhongshan 528400, China",
    "Biomedical Research Institute, Hunan University of Medicine, Huaihua 418000, China"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 8,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Haijun Zheng"
    },
    {
      "affs": [
        0
      ],
      "name": "Yanmiao Li"
    },
    {
      "affs": [
        1
      ],
      "name": "Kaixin Wu"
    },
    {
      "affs": [
        0
      ],
      "name": "Ting Ouyang"
    },
    {
      "affs": [
        2
      ],
      "name": "Nian Fu"
    },
    {
      "affs": [
        3
      ],
      "name": "Qinfang Zheng"
    },
    {
      "affs": [
        2
      ],
      "name": "Zhiyong Cai"
    },
    {
      "affs": [
        0
      ],
      "name": "Yi Liu"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/bc10h7fm98w33.bib",
  "cited_by": 0,
  "doi": "10.3390/cosmetics13050226",
  "fulltext_url": "https://www.mdpi.com/2079-9284/13/5/226",
  "id": "bc10h7fm98w33",
  "issns": [
    "2079-9284"
  ],
  "landing_url": "https://doi.org/10.3390/cosmetics13050226",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "QD1-999"
    ],
    [
      "openalex",
      "2105|TiO2 Photocatalysis and Solar Cells"
    ]
  ],
  "openalex": "W7206212759",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-01",
  "publisher": "MDPI AG",
  "ris": "https://research.draconitic.com/paper/bc10h7fm98w33.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T14:21:26Z",
      "native_id": "0a6b1e65e6cf4e9080bba50f2489d5a5",
      "source": "doaj",
      "url": "https://doi.org/10.3390/cosmetics13050226"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "lcc:QD1-999",
      "subfield": "general"
    },
    {
      "field": "medicine",
      "origin": "journal-openalex:2708|Skin Protection and Aging",
      "subfield": "general"
    }
  ],
  "title": "Mesoporous Silica-Supported TiO₂ Composite Sunscreen: Combining Low Whitening, Reduced Photoactivity, and Favorable Cytocompatibility",
  "title_text": "Mesoporous Silica-Supported TiO₂ Composite Sunscreen: Combining Low Whitening, Reduced Photoactivity, and Favorable Cytocompatibility",
  "type": "peer-reviewed",
  "updated_at": "2026-10-31T14:21:26Z",
  "url": "https://research.draconitic.com/paper/bc10h7fm98w33",
  "venue": "Cosmetics",
  "versions": []
}