{
  "abstract": "Comparing the effects of an out-of-bed armchair position versus an in-bed semi-recumbent position on oxygenation in spontaneously breathing intensive care unit (ICU) patients, receiving respiratory support is a common practice with limited supported evidence. A single-center randomized controlled trial in spontaneously breathing adult ICU patients receiving invasive pressure support ventilation, high-flow nasal oxygen, or non-invasive ventilation. Patients were assigned to armchair or semi-recumbent in-bed positioning for 3 h. Arterial blood gasses were obtained immediately before and after positioning. PaO2/FiO2 (P/F) changes were analyzed with a linear mixed-effects model including group, time, and their interaction, adjusted for stratification variables. 284 patients were randomized (146 and 138 in the armchair and bed groups, respectively). Baseline P/F ratios did not differ between groups. A significant interaction between group and time was observed (p = 0.002). In the armchair group, the P/F ratio increased by 13 mm Hg (95% CI 1–24), whereas it decreased by 13 mm Hg (95% CI − 25 to − 1) in the bed group. The post-positioning marginal mean P/F ratio was higher in the armchair group (241 mm Hg, 95% CI 214–268) than in the bed group (206 mm Hg, 95% CI 179–233; p = 0.004). No serious adverse events occurred. Minor adverse events were more frequent in the armchair group but had minimal impact on positioning duration. In spontaneously breathing ICU patients receiving respiratory support, out-of-bed armchair positioning was associated with higher oxygenation after 3 h than remaining in a semi-recumbent position, with no serious adverse events observed. NCT04446559.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 14,
  "authors": [
    {
      "name": "Guillaume Fossat"
    },
    {
      "name": "Lucie Muller"
    },
    {
      "name": "Aline Seguin"
    },
    {
      "name": "Armelle Mathonnet"
    },
    {
      "name": "Séverine Pinos"
    },
    {
      "name": "Toufik Kamel"
    },
    {
      "name": "François Barbier"
    },
    {
      "name": "Céline Loiseau"
    },
    {
      "name": "Marion Guemann"
    },
    {
      "name": "Léa Courtes"
    },
    {
      "name": "Cécile Fossat"
    },
    {
      "name": "Grégoire Muller"
    },
    {
      "name": "Mai-Anh Nay"
    },
    {
      "name": "Thierry Boulain"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/bck1e6tr0ry1x.bib",
  "cited_by": 3,
  "doi": "10.1007/s00134-026-08453-y",
  "fulltext_url": null,
  "id": "bck1e6tr0ry1x",
  "issns": [
    "0342-4642",
    "1432-1238"
  ],
  "landing_url": "https://normandie-univ.hal.science/hal-05835551v1",
  "language": "en",
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.sdv"
    ],
    [
      "openalex",
      "2740|Respiratory Support and Mechanisms"
    ]
  ],
  "openalex": "W7161567347",
  "pdf_url": "https://link.springer.com/content/pdf/10.1007/s00134-026-08453-y.pdf",
  "pmcid": null,
  "pmid": "42149248",
  "published": "2026-10-22",
  "publisher": "Springer Verlag",
  "ris": "https://research.draconitic.com/paper/bck1e6tr0ry1x.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:18:01Z",
      "native_id": "hal-05835551",
      "source": "hal",
      "url": "https://normandie-univ.hal.science/hal-05835551v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "hal:0.sdv",
      "subfield": "general"
    }
  ],
  "title": "Effects of Out-of-Bed Armchair Positioning on Oxygenation in Spontaneously Breathing ICU Patients Receiving Respiratory Support: A Randomized Controlled Trial",
  "title_text": "Effects of Out-of-Bed Armchair Positioning on Oxygenation in Spontaneously Breathing ICU Patients Receiving Respiratory Support: A Randomized Controlled Trial",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:18:01Z",
  "url": "https://research.draconitic.com/paper/bck1e6tr0ry1x",
  "venue": "Intensive Care Medicine",
  "versions": []
}