{
  "abstract": "Background: In the traditional treatment of overactive bladder (OAB) with transcutaneous posterior tibial nerve stimulation (TTNS), physical therapists currently use only transcutaneous electrical nerve stimulation (TENS). However, the literature has commonly replaced TENS with diadynamic currents for various musculoskeletal pain syndromes. Moreover, no literature describes the use of diadynamic currents in the TTNS procedure. Therefore, our study aimed to determine the efficacy of diadynamic currents (DDC) versus TENS for TTNS in OAB Treatment. Methodology: A randomized controlled trial was conducted among female patients with OAB aged 18–80 years. Subjects were randomly allocated to control and experimental groups. Participants in the control group received TTNS with TENS, and those in the experimental group underwent TTNS using DDC. Both groups received 8 TTNS sessions, two per week for 4 weeks. We measured pre- and post-intervention improvements using the International Consultation on Incontinence Questionnaire (ICIQ) for OAB and the ICIQ OAB Quality of Life (QOL). The study is registered with the Clinical Trials Registry of India under registration number CTRI/2025/12/099269. Results: The mean age of the included sample was 59.75 years. Pre- and post-intervention ICIQ-OAB and ICIQ-OAB QOL scores showed significant improvements in disease symptoms and quality of life among patients with OAB in both the control and experimental groups. Comparison of improvements between the two groups on the ICIQ questionnaires showed no significant difference (p-values of 0.87 and 0.95). Correlations between patient-related characteristics and improvements in outcome measures were also not significant. Conclusion: Eight sessions of TENS and DDC, combined with conventional physical therapy, including Kegel and breathing exercises, can reduce OAB symptoms and improve QOL in subjects with OAB syndrome. Diadynamic current can be used as an adjunct to conventional TENS in TTNS for treating OAB syndrome.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Medical Rehabilitation Science, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia",
    "Department of Neurorehabilitation, Krishna Institute of Medical Sciences, Secunderabad, Telangana, India",
    "Sr Consultant Urogynecology, Department of Urogynecology, Krishna Institute of Medical Sciences, Secunderabad, Telangana, India",
    "Physiotherapy Department, Armed Forces Hospital Southern Region Rehabilitation Health Services, Khamis Mushait, Saudi Arabia"
  ],
  "article_type": "Research Article",
  "arxiv": null,
  "author_total": 11,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Jaya Shanker Tedla"
    },
    {
      "affs": [
        1
      ],
      "name": "Sneha Latha Lalaji"
    },
    {
      "affs": [
        2
      ],
      "name": "Ajaya Kumar Midde"
    },
    {
      "affs": [
        3
      ],
      "name": "Nirmala A. Papalkar"
    },
    {
      "name": "N. Bindhu Priya"
    },
    {
      "name": "Devika Rani Sangadala"
    },
    {
      "name": "Ravi Shankar Reddy"
    },
    {
      "name": "Debjani Mukherjee"
    },
    {
      "name": "Ahlam Mohammed Alamri"
    },
    {
      "name": "Abdullah Suwayyid Alzahrani"
    },
    {
      "name": "Najla Awn Alhadi"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/bcwyr19n5fhqs.bib",
  "cited_by": 0,
  "doi": "10.1371/journal.pone.0362118",
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  "id": "bcwyr19n5fhqs",
  "issns": [
    "1932-6203"
  ],
  "landing_url": "https://doi.org/10.1371/journal.pone.0362118",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2748|Urinary Bladder and Prostate Research"
    ],
    [
      "plos",
      "/Biology and life sciences/Anatomy/Renal system/Bladder"
    ],
    [
      "plos",
      "/Biology and life sciences/Neuroscience/Cognitive science/Cognitive psychology/Perception/Sensory perception"
    ],
    [
      "plos",
      "/Biology and life sciences/Neuroscience/Sensory perception"
    ],
    [
      "plos",
      "/Biology and life sciences/Psychology/Cognitive psychology/Perception/Sensory perception"
    ],
    [
      "plos",
      "/Medicine and health sciences/Anatomy/Renal system/Bladder"
    ],
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      "plos",
      "/Medicine and health sciences/Clinical medicine/Clinical trials/Randomized controlled trials"
    ],
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      "plos",
      "/Medicine and health sciences/Endocrinology/Endocrine disorders/Diabetes mellitus"
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      "/Medicine and health sciences/Health care/Physiotherapy"
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      "plos",
      "/Medicine and health sciences/Health care/Quality of life"
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      "/Medicine and health sciences/Urology/Incontinence"
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  "openalex": "W7225422646",
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  "published": "2026-11-06",
  "publisher": "Public Library of Science",
  "ris": "https://research.draconitic.com/paper/bcwyr19n5fhqs.ris",
  "sources": [
    {
      "first_seen": "2026-11-07T12:20:24Z",
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  "subjects": [
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  "title": "Efficacy of diadynamic currents versus transcutaneous electrical nerve stimulation for transcutaneous tibial nerve stimulation in subjects with overactive bladder syndrome: A double-blind randomized controlled trial",
  "title_text": "Efficacy of diadynamic currents versus transcutaneous electrical nerve stimulation for transcutaneous tibial nerve stimulation in subjects with overactive bladder syndrome: A double-blind randomized controlled trial",
  "type": "peer-reviewed",
  "updated_at": "2026-11-08T12:20:48Z",
  "url": "https://research.draconitic.com/paper/bcwyr19n5fhqs",
  "venue": "PLOS One",
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}