{
  "abstract": "Among South African women using oral HIV preexposure prophylaxis, we compared a urine tenofovir point-of-care test with dried blood spot tenofovir diphosphate concentrations for recent vs longer-term adherence and assessed acceptability. The test demonstrated 76% accuracy, 100% sensitivity, and 69% specificity for high adherence (tenofovir diphosphate ≥700 fmol/punch) and was highly acceptable.\n\nClinical Trials Registration: NCT04038060.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": "brief report",
  "arxiv": null,
  "author_total": 10,
  "authors": [
    {
      "name": "Nicole Poovan",
      "orcid": "0009-0002-6675-6241"
    },
    {
      "name": "Jennifer Velloza",
      "orcid": "0000-0001-7242-7415"
    },
    {
      "name": "Nontokozo H Ndlovu",
      "orcid": "0009-0009-2121-3658"
    },
    {
      "name": "Allison Meisner",
      "orcid": "0000-0001-5177-7635"
    },
    {
      "name": "Cole Grabow",
      "orcid": "0000-0003-2006-8654"
    },
    {
      "name": "Monica Gandhi",
      "orcid": "0000-0002-7025-1994"
    },
    {
      "name": "Deborah Donnell",
      "orcid": "0000-0002-0587-7480"
    },
    {
      "name": "Sybil Hosek"
    },
    {
      "name": "Connie Celum"
    },
    {
      "name": "Sinead Delany-Moretlwe",
      "orcid": "0000-0003-0376-1019"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/be1dqy6zez99j.bib",
  "cited_by": 0,
  "doi": "10.1093/ofid/ofag612",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13728699/?tool=EBI",
  "id": "be1dqy6zez99j",
  "issns": [
    "2328-8957"
  ],
  "landing_url": "https://europepmc.org/article/PMC/PMC13728699",
  "language": "eng",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "AcademicSubjects/MED00290"
    ],
    [
      "heading",
      "Brief Report"
    ],
    [
      "heading",
      "Clinical Trials and Therapeutics"
    ],
    [
      "openalex",
      "2725|HIV/AIDS Research and Interventions"
    ]
  ],
  "openalex": "W7225146695",
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13728699/pdf/?tool=EBI",
  "pmcid": "PMC13728699",
  "pmid": "42979201",
  "published": "2026-11-01",
  "publisher": "Oxford University Press",
  "ris": "https://research.draconitic.com/paper/be1dqy6zez99j.ris",
  "sources": [
    {
      "first_seen": "2026-11-04T15:20:46Z",
      "native_id": "PMC:PMC13728699",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13728699"
    },
    {
      "first_seen": "2026-11-07T12:21:38Z",
      "native_id": "PMC13728699",
      "source": "pmc",
      "url": "https://doi.org/10.1093/ofid/ofag612"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2725|HIV/AIDS Research and Interventions",
      "subfield": "infectious-disease"
    }
  ],
  "title": "Optimizing Preexposure Prophylaxis Adherence: Evaluating Point-of-Care Urine Tenofovir Testing and Tailored Counseling Among Young South African Women",
  "title_text": "Optimizing Preexposure Prophylaxis Adherence: Evaluating Point-of-Care Urine Tenofovir Testing and Tailored Counseling Among Young South African Women",
  "type": "peer-reviewed",
  "updated_at": "2026-11-07T12:21:38Z",
  "url": "https://research.draconitic.com/paper/be1dqy6zez99j",
  "venue": "Open forum infectious diseases",
  "versions": []
}