{
  "abstract": "We report a case of a 60-year-old woman with biopsy-proven, proteinase-3 (PR3)-antineutrophil cytoplasmic antibody (ANCA)-associated granulomatosis with polyangiitis (GPA), diagnosed six years earlier, who presented with right lower thoracic pain during a disease relapse. The relapse was supported by serological reactivation with a markedly elevated anti-PR3 level, a raised erythrocyte sedimentation rate (ESR) (88 mm/h), and elevated C-reactive protein (CRP) (48 mg/L). Unenhanced computed tomography (CT) showed no pulmonary parenchymal abnormality but revealed soft-tissue infiltration of the anterior and right lateral paravertebral mediastinal fat extending from T4-T5 to T10-T11, without adjacent osseous involvement. Fluorine-18 (18F)-fluorodeoxyglucose (FDG) positron emission tomography/CT (PET/CT) demonstrated intense uptake within the lesion, with a maximum standardized uptake value (SUVmax) of 12.06. Given the differential diagnoses of lymphoma and other granulomatous disease, the lesion was interpreted as a presumed GPA-related paravertebral inflammatory pseudotumor; it was not biopsied. After rituximab and methylprednisolone, the patient achieved complete clinical and biological remission with ANCA seroconversion, and follow-up FDG PET/CT at three months showed complete resolution of the abnormal uptake. Because neither FDG avidity nor treatment response was specific, the presumed diagnosis could not be confirmed histologically in this case.",
  "abstract_shown": true,
  "affiliations": [
    "Radiology, Erasmus Hospital, Bruxelles, BEL",
    "Nuclear Medicine, Erasmus Hospital, Bruxelles, BEL"
  ],
  "article_type": "case report",
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Yasmina Hamida El Khloufi"
    },
    {
      "affs": [
        1
      ],
      "name": "Redouane Soussi"
    },
    {
      "affs": [
        0
      ],
      "name": "Pascale Bohy"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/be46amxagjfac.bib",
  "cited_by": 0,
  "doi": "10.7759/cureus.117516",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13735414/",
  "id": "be46amxagjfac",
  "issns": [
    "2168-8184"
  ],
  "landing_url": "https://doi.org/10.7759/cureus.117516",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Internal Medicine"
    ],
    [
      "heading",
      "Nuclear Medicine"
    ],
    [
      "heading",
      "Radiology"
    ],
    [
      "openalex",
      "2745|Vasculitis and related conditions"
    ]
  ],
  "openalex": "W7220693126",
  "pdf_url": "https://www.cureus.com/articles/534998-presumed-paravertebral-inflammatory-pseudotumor-in-relapsing-granulomatosis-with-polyangiitis-fluorodeoxyglucose-fdg-positron-emission-tomographycomputed-tomography-petct-findings-and-complete-metabolic-response-to-rituximab-based-therapy.pdf",
  "pmcid": "PMC13735414",
  "pmid": "42991188",
  "published": "2026-10-05",
  "publisher": "Cureus Inc.",
  "ris": "https://research.draconitic.com/paper/be46amxagjfac.ris",
  "sources": [
    {
      "first_seen": "2026-11-09T12:21:06Z",
      "native_id": "PMC13735414",
      "source": "pmc",
      "url": "https://doi.org/10.7759/cureus.117516"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "heading:Radiology",
      "subfield": "imaging"
    }
  ],
  "title": "Presumed Paravertebral Inflammatory Pseudotumor in Relapsing Granulomatosis With Polyangiitis: Fluorodeoxyglucose (FDG) Positron Emission Tomography/Computed Tomography (PET/CT) Findings and Complete Metabolic Response to Rituximab-Based Therapy",
  "title_text": "Presumed Paravertebral Inflammatory Pseudotumor in Relapsing Granulomatosis With Polyangiitis: Fluorodeoxyglucose (FDG) Positron Emission Tomography/Computed Tomography (PET/CT) Findings and Complete Metabolic Response to Rituximab-Based Therapy",
  "type": "peer-reviewed",
  "updated_at": "2026-11-09T12:21:06Z",
  "url": "https://research.draconitic.com/paper/be46amxagjfac",
  "venue": "Cureus",
  "versions": []
}