{
  "abstract": "Introduction\n\nMeningioma is one of the most common central nervous system tumors; however, metastatic lesions are extremely rare. Particularly, hepatic metastasis from meningioma is uncommon, and its diagnosis and optimal management remain undefined.Case presentation\n\nA 70-year-old man with a history of left parietal meningioma resection in 2011 and gamma knife therapy for recurrence in the left lateral ventricle in June 2025. A PET-CT scan performed for cancer screening in June 2025 revealed abnormal fluorodeoxyglucose uptake in segment 8 of the liver, with a maximum standardized uptake value of 6.2. CT, and MRI revealed multiple hepatic masses. All tumor markers were within normal ranges. A percutaneous liver biopsy indicated a spindle cell tumor; however, the diagnosis remained inconclusive. For diagnostic and therapeutic purposes, partial hepatectomy of segments 6 and 8 and cholecystectomy were performed. Histopathological examination revealed proliferating spindle-shaped tumor cells arranged in fascicles. Immunohistochemical staining was positive for vimentin, epithelial membrane antigen, and somatostatin receptor 2, confirming the diagnosis of hepatic metastasis from meningioma. The postoperative course was uneventful, and the patient was discharged in good condition.Conclusions\n\nHepatic metastasis from meningioma is extremely rare; however, it should be considered in the differential diagnosis of hepatic tumors in patients with a history of meningioma. Surgical resection is valuable in establishing a definitive diagnosis and achieving local disease control.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Surgery, Kagoshima Kouseiren Hospital, Kagoshima, Kagoshima, Japan.",
    "Department of Pathology, Kagoshima Kouseiren Hospital, Kagoshima, Kagoshima, Japan.",
    "Department of Hepatology, Kagoshima Kouseiren Hospital, Kagoshima, Kagoshima, Japan."
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Yuki Hirase",
      "orcid": "0009-0007-5676-1270"
    },
    {
      "affs": [
        0
      ],
      "name": "Haruhi Fukuhisa"
    },
    {
      "affs": [
        0
      ],
      "name": "Akihiko Sakamoto"
    },
    {
      "affs": [
        0
      ],
      "name": "Masahiko Sakoda"
    },
    {
      "affs": [
        1
      ],
      "name": "Sumika Matsukita"
    },
    {
      "affs": [
        2
      ],
      "name": "Takuya Hiwaki"
    },
    {
      "affs": [
        0
      ],
      "name": "Shigeho Maenohara"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/bj3hwby6x8pgr.bib",
  "cited_by": 0,
  "doi": "10.70352/scrj.cr.26-0401",
  "fulltext_url": "https://europepmc.org/articles/PMC13677216",
  "id": "bj3hwby6x8pgr",
  "issns": [
    "2198-7793"
  ],
  "landing_url": "https://europepmc.org/article/MED/42894863",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2713|Meningioma and schwannoma management"
    ]
  ],
  "openalex": "W7221903129",
  "pdf_url": "https://europepmc.org/articles/PMC13677216?pdf=render",
  "pmcid": "PMC13677216",
  "pmid": "42894863",
  "published": "2026-10-16",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/bj3hwby6x8pgr.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:33Z",
      "native_id": "MED:42894863",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42894863"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2713|Meningioma and schwannoma management",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "Hepatic Metastasis of Meningioma Treated with Partial Hepatectomy: A Case Report.",
  "title_text": "Hepatic Metastasis of Meningioma Treated with Partial Hepatectomy: A Case Report.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:19:33Z",
  "url": "https://research.draconitic.com/paper/bj3hwby6x8pgr",
  "venue": "Surgical case reports",
  "versions": []
}