{
  "abstract": "Background To identify distinct clinical phenotypes among older adults presenting to the emergency department (ED) using an unsupervised machine learning approach and to characterize their clinical characteristics, healthcare utilization patterns, and discharge outcomes. Methods The retrospective study was based on secondary analysis of data from the “Program for the Taiwan Triage and Acuity Scale (TTAS) for Elderly in Emergency Department”. A total of 1,617 non-traumatic older patients (aged ≥ 65 years) presenting to the emergency department (ED) were included. K-prototypes cluster analysis, an unsupervised machine learning approach, was used to identify distinct clinical phenotypes. Results The K-prototypes clustering algorithm identified three distinct phenotypes: Cluster 1 (frail and highly comorbid; 31.6%), Cluster 2 (younger and functionally preserved; 32.2%), and Cluster 3 (metabolically burdened; 36.2%). Cluster 1 was characterized by the highest median ED costs (4,191.5 points) and the longest LOS (median 8 days). Although 77.1% of patients in Cluster 2 were discharged from the ED, those requiring hospitalization had the highest proportion of in-hospital death or against advice discharge (AAD) (17.6%). Cluster 3 demonstrated obesity and metabolic risks but maintained relatively intact functional status. Conclusions Machine learning clustering identified distinct clinical phenotypes among older adults presenting to the ED. These phenotypes may provide additional insights into the heterogeneity of this population and could help inform future phenotype-oriented risk stratification and individualized emergency care.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Emergency Medicine, Chang Gung Memorial Hospital, Linkou and College of Medicine, Chang Gung University"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Shou-Chien Hsu"
    },
    {
      "affs": [
        0
      ],
      "name": "Cheng-Yu Chien"
    },
    {
      "affs": [
        0
      ],
      "name": "Hsiao-Jung Tseng"
    },
    {
      "affs": [
        0
      ],
      "name": "Yi-Chia Su"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/bje6jn1hj7tqj.bib",
  "cited_by": 0,
  "doi": "10.1186/s12877-026-08052-y",
  "fulltext_url": "https://doi.org/10.1186/s12877-026-08052-y",
  "id": "bje6jn1hj7tqj",
  "issns": [
    "1471-2318"
  ],
  "landing_url": "https://doi.org/10.1186/s12877-026-08052-y",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "RC952-954.6"
    ],
    [
      "openalex",
      "2711|Emergency and Acute Care Studies"
    ]
  ],
  "openalex": "W7171485689",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-07-01",
  "publisher": "BMC",
  "ris": "https://research.draconitic.com/paper/bje6jn1hj7tqj.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:46:29Z",
      "native_id": "edeb6d01029b4fc9ad3e955ee415b356",
      "source": "doaj",
      "url": "https://doi.org/10.1186/s12877-026-08052-y"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2711|Emergency and Acute Care Studies",
      "subfield": "general"
    }
  ],
  "title": "Cluster analysis of elderly emergency department patients in Taiwan: identifying clinical profiles and healthcare utilization patterns",
  "title_text": "Cluster analysis of elderly emergency department patients in Taiwan: identifying clinical profiles and healthcare utilization patterns",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:46:29Z",
  "url": "https://research.draconitic.com/paper/bje6jn1hj7tqj",
  "venue": "BMC Geriatrics",
  "versions": []
}