{
  "abstract": "The detection and quantification of nanoplastics (NPLs) in complex matrices remain a major analytical challenge. In this study, gold-labelled NPLs consisting of a gold nanoparticle core covered by a polystyrene (PS) shell were designed, enabling sensitive quantification by single-particle inductively coupled plasma mass spectrometry (SP-ICP-MS). Optimized conditions yielded NPLs containing one single gold nanoparticle per NPL and exhibiting surface functionalization. These NPLs fulfill key criteria for realistic NPLs models, combining: the use of an environmentally relevant polymer (PS), the exact control over their chemical composition, a density comparable to that of native PS particles despite gold-labelling, and a strong traceability. The strategy applied here demonstrates unprecedented sensitivity, with a limit of detection of 2.8 x 105 NPL L−1 (0.21 ng of NPLs), enabling detection of environmentally realistic concentrations. The method validation performed with NPLs-spiked Daphnia magna achieved recovery rates close to 100%. Exposure experiments revealed a dose-dependent ingestion of NPLs, up to 8.5 x 105 particles/daphnid (64 ng of NPLs) after 48 h. This study combines gold-labelling, precise chemical control, and environmental relevance to enable accurate NPLs quantification in organisms at low, realistic concentrations, paving the way for robust ecotoxicological assessments.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 8,
  "authors": [
    {
      "name": "Sophie Miguel"
    },
    {
      "name": "Lea Spitzer"
    },
    {
      "name": "Antoine Aynard"
    },
    {
      "name": "Javier Jiménez Lamana"
    },
    {
      "name": "Séverine Le Faucheur"
    },
    {
      "name": "Virginie Pellerin"
    },
    {
      "name": "Bruno Grassl"
    },
    {
      "name": "Stéphanie Reynaud"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/bknf2xf77kp05.bib",
  "cited_by": 0,
  "doi": "10.1016/j.jhazmat.2026.142924",
  "fulltext_url": null,
  "id": "bknf2xf77kp05",
  "issns": [
    "0304-3894",
    "1873-3336"
  ],
  "landing_url": "https://hal.science/hal-05757638v1",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.chim"
    ],
    [
      "hal",
      "0.sde"
    ],
    [
      "openalex",
      "2310|Microplastics and Plastic Pollution"
    ]
  ],
  "openalex": "W7167619809",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-21",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/bknf2xf77kp05.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:37Z",
      "native_id": "hal-05757638",
      "source": "hal",
      "url": "https://hal.science/hal-05757638v1"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "hal:0.chim",
      "subfield": "general"
    },
    {
      "field": "earth",
      "origin": "hal:0.sde",
      "subfield": "environmental-science"
    }
  ],
  "title": "Gold-labelled nanoplastics models: Synthesis, detection, and quantification by SP-ICP-MS in Daphnia magna",
  "title_text": "Gold-labelled nanoplastics models: Synthesis, detection, and quantification by SP-ICP-MS in Daphnia magna",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:37Z",
  "url": "https://research.draconitic.com/paper/bknf2xf77kp05",
  "venue": "Journal of Hazardous Materials",
  "versions": []
}