{
  "abstract": "Contamination of water and soil by heavy metal ions is a major global concern because these ions are toxic and persist in the environment for long periods. A new, effective fluorescent sensor based on a fluoroquinolone was developed for detecting zinc ions (Zn2+) with a turn-on signal. When Zn2+ ions are gradually added to the fluoroquinolone solution, the fluorescence intensity increases due to an internal charge transfer mechanism. We evaluated the detection of Zn2+ ions using the fluorescence probe in various solvents and across different pH conditions. The key results showed that the fluorescent probe demonstrated a strong preference for detecting Zn2+ ions in ethanol, maintaining accuracy despite the presence of other metal ions, and exhibited enhanced sensitivity. The developed sensor achieved a remarkably low detection limit of 1 nM for Zn2+ ions, outperforming earlier reported sensors. Fluorescence measurements exhibited a consistent linear correlation for Zn2+ concentrations between 1 nM and 15 µM. Furthermore, spectrophotometric data showed increased absorbance peaks upon addition of Zn2+ to the fluoroquinolone solution, confirming the creation of a fluoroquinolone–Zn2+ complex. The suggested probe was successfully applied to detect Zn2+ ions in wastewater and drinking water samples, achieving recovery rates ranging from 97.0% to 102.75%. More interestingly, binding to Zn2+ leads to significant changes in the fluorescence lifetime of the proposed probe, which can be used to visualize Zn2+ ions in A549 cells via Confocal fluorescence microscopy. The reported chemosensor with fluoroquinolone is an effective and economical system for real-time monitoring of Zn2+ ions.",
  "abstract_shown": true,
  "affiliations": [
    "Green Technology, Department of Chemistry, SIMATS Engineering, Saveetha Institute of Medical and Technical Sciences, Saveetha University 602105 Tamil Nadu India",
    "Faculty of Science, Department of Chemistry, Chulalongkorn University Bangkok 10330 Thailand",
    "Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER) Guwahati & Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, Govt. of India Sila Katamur (Halugurisuk) Changsari, Kamrup Assam 781101 India",
    "Interdisciplinary Institute of Indian System of Medicine (IIISM), Directorate of Research, SRM Institute of Science and Technology Kattankulathur 603203 Tamil Nadu India",
    "Department of Chemistry, SRM Institute of Science and Technology, Ramapuram Campus India"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Daniel Arulraj Abraham",
      "orcid": "0000-0002-3314-6001"
    },
    {
      "affs": [
        1
      ],
      "name": "Ravikumar Ayyanu"
    },
    {
      "affs": [
        2
      ],
      "name": "Ellairaja Sundaram"
    },
    {
      "affs": [
        3
      ],
      "name": "Balasubramani Govindasamy"
    },
    {
      "affs": [
        4
      ],
      "name": "A. Anand Babu Christus"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/bn8k5ncb8xjhm.bib",
  "cited_by": 0,
  "doi": "10.1039/d6ra00838k",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13659653/?tool=EBI",
  "id": "bn8k5ncb8xjhm",
  "issns": [
    "2046-2069"
  ],
  "landing_url": "https://europepmc.org/article/PMC/PMC13659653",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Chemistry"
    ],
    [
      "openalex",
      "1607|Molecular Sensors and Ion Detection"
    ]
  ],
  "openalex": "W7221721862",
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13659653/pdf/?tool=EBI",
  "pmcid": "PMC13659653",
  "pmid": "42871970",
  "published": "2026-10-13",
  "publisher": "Royal Society of Chemistry",
  "ris": "https://research.draconitic.com/paper/bn8k5ncb8xjhm.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:21Z",
      "native_id": "PMC:PMC13659653",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13659653"
    },
    {
      "first_seen": "2026-11-01T12:23:37Z",
      "native_id": "PMC13659653",
      "source": "pmc",
      "url": "https://doi.org/10.1039/d6ra00838k"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1607|Molecular Sensors and Ion Detection",
      "subfield": "physical"
    }
  ],
  "title": "An effective fluoroquinolone-based fluorescent probe for ultrasensitive Zn2+ detection exhibiting “turn-on” fluorescence",
  "title_text": "An effective fluoroquinolone-based fluorescent probe for ultrasensitive Zn2+ detection exhibiting “turn-on” fluorescence",
  "type": "peer-reviewed",
  "updated_at": "2026-11-02T12:20:51Z",
  "url": "https://research.draconitic.com/paper/bn8k5ncb8xjhm",
  "venue": "RSC advances",
  "versions": []
}