{
  "abstract": "Background: Methicillin-resistant Staphylococcus aureus (MRSA) is an important driver of antimicrobial resistance (AMR) globally; however, existing surveillance systems are largely hospital-focused, potentially underestimating the burden and transmission dynamics of MRSA in community settings. Methods: A cross-sectional study was conducted among apparently healthy children aged 1–59 months in northeastern Nigeria. Nasopharyngeal swabs were cultured for S. aureus using standard microbiological methods. Methicillin resistance was determined by cefoxitin disk diffusion. Result: Staphylococcus aureus was isolated from 122 (52.1%; 95% CI: 45.8–58.5%) of the 234 children included in this study. Among these, 31 isolates were classified as MRSA, corresponding to a prevalence of 25.4% (95% CI: 18.5–33.8%) among isolates and 13.2% (95% CI: 9.5–18.2%) at the study population level. Cefoxitin zone diameters demonstrated a clear bimodal distribution, with MRSA clustering at lower diameters and MSSA at higher diameters, with minimal overlap around the CLSI breakpoint. Only 13.1% of isolates were within ±2 mm of the breakpoint, indicating limited classification ambiguity. Conclusions: MRSA carriage among healthy children in this community-based LMIC setting is substantial and may be missed in existing surveillance frameworks. These findings highlight the need to expand AMR surveillance beyond healthcare facilities to include community pediatric populations.",
  "abstract_shown": true,
  "affiliations": [
    "Corresponding author.",
    "Nigerian Institute of Medical Research, Nigeria"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 14,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Hafeez A. Adekola"
    },
    {
      "affs": [
        1
      ],
      "name": "Abideen O. Salako"
    },
    {
      "affs": [
        1
      ],
      "name": "Samson A. Luka"
    },
    {
      "affs": [
        1
      ],
      "name": "Sakinah O. Adewunmi"
    },
    {
      "affs": [
        1
      ],
      "name": "Ajoke O. Adagbada"
    },
    {
      "affs": [
        1
      ],
      "name": "Jacob I. Yisau"
    },
    {
      "affs": [
        1
      ],
      "name": "Oluwatoyin B. Awoderu"
    },
    {
      "affs": [
        1
      ],
      "name": "Vincent P. Gyang"
    },
    {
      "affs": [
        1
      ],
      "name": "Olusola Ajibaye"
    },
    {
      "affs": [
        1
      ],
      "name": "Toyosi Y. Raheem"
    },
    {
      "affs": [
        1
      ],
      "name": "Emelda E. Chukwu"
    },
    {
      "affs": [
        1
      ],
      "name": "Muinah A. Fowora"
    },
    {
      "affs": [
        1
      ],
      "name": "Tajudeen A. Bamidele"
    },
    {
      "affs": [
        1
      ],
      "name": "Oliver C. Ezechi"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/brcpb9xqb4jvd.bib",
  "cited_by": 0,
  "doi": "10.1016/j.microb.2026.100818",
  "fulltext_url": "http://www.sciencedirect.com/science/article/pii/S2950194626001640",
  "id": "brcpb9xqb4jvd",
  "issns": [
    "2950-1946"
  ],
  "landing_url": "https://doi.org/10.1016/j.microb.2026.100818",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "QR1-502"
    ],
    [
      "openalex",
      "2725|Antimicrobial Resistance in Staphylococcus"
    ]
  ],
  "openalex": "W7222923657",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-30",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/brcpb9xqb4jvd.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:43:45Z",
      "native_id": "dfc1e766405d46d48679388fc462a904",
      "source": "doaj",
      "url": "https://doi.org/10.1016/j.microb.2026.100818"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2725|Antimicrobial Resistance in Staphylococcus",
      "subfield": "infectious-disease"
    }
  ],
  "title": "Community MRSA reservoir in children in Adamawa State, Nigeria: Prevalence and phenotypic distribution analysis",
  "title_text": "Community MRSA reservoir in children in Adamawa State, Nigeria: Prevalence and phenotypic distribution analysis",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:43:45Z",
  "url": "https://research.draconitic.com/paper/brcpb9xqb4jvd",
  "venue": "The Microbe",
  "versions": []
}