{
  "abstract": "Introduction\n\nPandemic situation by severe acute respiratory syndrome coronavirus 2 and the associated disease (coronavirus disease 2019 [COVID-19]) presents broad challenges. Post-COVID-19 condition represents a continuum of persistent symptoms following the acute course. The World Health Organization (WHO) proposes a definition with at least one symptom persisting for 3 months postonset. Negative affection toward quality of life (QoL) is frequently reported. Patients with immune-mediated inflammatory diseases (IMIDs), such as inflammatory bowel disease (IBD) and rheumatic diseases (RDs) are of scientific interest as immunologic factors and immunosuppressive therapy might influence QoL in post-COVID-19 conditions.Methods\n\nAdult IMID patients (≥18 years) were offered participation in this study at our university outpatient center. Data collection was questionnaire-based and recorded individual COVID-19 history and persisting symptoms. QoL has been assessed by several standardized and validated patient-reported outcome measures (Short IBD Questionnaire and Patient Health Questionnaire 4, 5Q-5D-5L).Results\n\nA total of 156 patients were included (117 [75%] with IBD, 39 [25%] with RDs). Eighty-one patients (51%) reported a positive COVID-19 history, mostly with mild courses. Only two (2%) required hospitalization, one requiring intensive care. Seven (9%) reported no symptoms, while 20 (25%) met the WHO criterion for post-COVID-19 condition; 19 (23%) were still suffering from post-COVID-19 at the time of data acquisition. Mean/median global QoL scores (scale from 0 [=lowest] to 100 [=highest]) were 71.5/75 in patients without post-COVID-19, compared to 61.9/60 in those with the condition. A one-sided t-test showed a significant association between post-COVID-19 and lower QoL (P = 0.03).Conclusions\n\nA relevant fraction of IMID patients suffered from post-COVID-19 condition. This condition negatively impacted the individual QoL.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Oncology, Gastroenterology, Hepatology, Pneumology and Infectious Diseases, Division of Gastroenterology, University of Leipzig Medical Center, Germany.",
    "Medical Clinic III: Endocrinology, Nephrology and Rheumatology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Tobias Schlosser"
    },
    {
      "affs": [
        1
      ],
      "name": "Marco Krasselt"
    },
    {
      "affs": [
        0
      ],
      "name": "Martin Hecker"
    },
    {
      "affs": [
        0
      ],
      "name": "Babett Holler"
    },
    {
      "affs": [
        0
      ],
      "name": "Albrecht Hoffmeister"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/bvqc5c70sapp9.bib",
  "cited_by": 0,
  "doi": "10.4103/jgid.jgid_142_25",
  "fulltext_url": "https://europepmc.org/articles/PMC13679952",
  "id": "bvqc5c70sapp9",
  "issns": [
    "0974-777X",
    "0974-8245"
  ],
  "landing_url": "https://europepmc.org/article/MED/42899016",
  "language": "eng",
  "licence": "CC-BY-NC-SA",
  "licence_label": "CC BY-NC-SA",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-sa/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2728|Long-Term Effects of COVID-19"
    ]
  ],
  "openalex": "W7202070607",
  "pdf_url": "https://europepmc.org/articles/PMC13679952?pdf=render",
  "pmcid": "PMC13679952",
  "pmid": "42899016",
  "published": "2026-07-01",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/bvqc5c70sapp9.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:42Z",
      "native_id": "MED:42899016",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42899016"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2728|Long-Term Effects of COVID-19",
      "subfield": "neurology"
    }
  ],
  "title": "Post-COVID-19 Condition has High Prevalence in Patients with Immune-mediated Inflammatory Diseases and Negatively Impacts Quality of Life.",
  "title_text": "Post-COVID-19 Condition has High Prevalence in Patients with Immune-mediated Inflammatory Diseases and Negatively Impacts Quality of Life.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:19:42Z",
  "url": "https://research.draconitic.com/paper/bvqc5c70sapp9",
  "venue": "Journal of global infectious diseases",
  "versions": []
}