{
  "abstract": "Objective\n\nPostoperative nausea and vomiting (PONV) remains a common complication in the post-anaesthesia care unit (PACU) and negatively affects patient comfort and satisfaction. In routine clinical practice, identifying perioperative factors associated with early PONV may help optimize preventive strategies and guide anesthetic management. This study primarily aimed to evaluate PONV during the first postoperative hour and associated perioperative factors, and secondarily to describe PONV at later postoperative time points and antiemetic practices.Methods\n\nThis retrospective observational study evaluated adult patients who underwent elective surgery under general or regional anaesthesia from January to December 2021. After applying eligibility and complete-case criteria, 584 ASA I-III patients were included. Demographic characteristics, anesthetic techniques, surgical features, Apfel risk factors, antiemetic prophylaxis, rescue antiemetic use, and binary PONV data at postoperative hours 1, 6, 12, and 24 were assessed.Results\n\nPONV occurred in 128 patients (22%) during the first postoperative hour and decreased at later postoperative time points. In univariate analyses, first-hour PONV was associated with general anaesthesia, inhalational anesthetic use, perioperative opioid use, female sex, non-smoking status, and perioperative medication-related variables (P < 0.05). The adjusted analysis suggested that early PONV in routine clinical practice reflects an overlapping, multifactorial pattern rather than the effect of a single dominant perioperative factor.Conclusion\n\nFirst-hour PONV remained a clinically relevant problem in routine perioperative care despite the common use of prophylactic antiemetics. These findings highlight the importance of careful early postoperative monitoring and individualized risk-based preventive strategies in daily anaesthesia practice.",
  "abstract_shown": true,
  "affiliations": [
    "Necmettin Erbakan University Faculty of Medicine, Department of Pain Medicine, Konya, Türkiye.",
    "Süleyman Demirel University Faculty of Medicine, Department of Anaesthesiology and Reanimation, Isparta, Türkiye.",
    "Süleyman Demirel University Faculty of Medicine, Department of Family Medicine, Isparta, Türkiye."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Onurcan Balık",
      "orcid": "0000-0002-5320-9874"
    },
    {
      "affs": [
        1
      ],
      "name": "Filiz Alkaya Solmaz",
      "orcid": "0000-0001-5772-6708"
    },
    {
      "affs": [
        1
      ],
      "name": "Mustafa Soner Özcan",
      "orcid": "0000-0003-0385-2308"
    },
    {
      "affs": [
        2
      ],
      "name": "Gökçe İşcan",
      "orcid": "0000-0003-0848-5201"
    },
    {
      "affs": [
        1
      ],
      "name": "Pakize Kırdemir",
      "orcid": "0000-0001-7784-1818"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/bw0vmpewkjgwc.bib",
  "cited_by": 0,
  "doi": "10.4274/tjar.2026.262558",
  "fulltext_url": "https://europepmc.org/articles/PMC13725887",
  "id": "bw0vmpewkjgwc",
  "issns": [
    "2667-677X",
    "2667-6370"
  ],
  "landing_url": "https://europepmc.org/article/MED/42969163",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Original Article"
    ],
    [
      "openalex",
      "2746|Nausea and vomiting management"
    ]
  ],
  "openalex": "W7224945834",
  "pdf_url": "https://europepmc.org/articles/PMC13725887?pdf=render",
  "pmcid": "PMC13725887",
  "pmid": "42969163",
  "published": "2026-10-01",
  "publisher": "Turkish Society of Anaesthesiology and Reanimation",
  "ris": "https://research.draconitic.com/paper/bw0vmpewkjgwc.ris",
  "sources": [
    {
      "first_seen": "2026-11-03T15:20:53Z",
      "native_id": "MED:42969163",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42969163"
    },
    {
      "first_seen": "2026-11-05T12:22:20Z",
      "native_id": "PMC13725887",
      "source": "pmc",
      "url": "https://doi.org/10.4274/tjar.2026.262558"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2746|Nausea and vomiting management",
      "subfield": "surgery"
    }
  ],
  "title": "Early Postoperative Nausea and Vomiting in Routine Clinical Practice: A Retrospective Observational Study of Associated Perioperative Factors and Prophylactic Practices.",
  "title_text": "Early Postoperative Nausea and Vomiting in Routine Clinical Practice: A Retrospective Observational Study of Associated Perioperative Factors and Prophylactic Practices.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-06T12:21:58Z",
  "url": "https://research.draconitic.com/paper/bw0vmpewkjgwc",
  "venue": "Turkish journal of anaesthesiology and reanimation",
  "versions": []
}