{
  "abstract": "We compared the immunogenicity of three licensed egg-based inactivated influenza vaccines, including TetrAnflu (Sinovac quadrivalent), Fluarix Tetra (GSK quadrivalent), and Vaxigrip (Sanofi trivalent), in adult healthcare workers in Hong Kong during the 2025/26 season. Age- and sex-matched recipients (n=30-40 per group) with paired pre- and post-vaccination sera were identified from an ongoing cohort. Hemagglutination-inhibition assays were performed against the egg-propagated 2025/26 vaccine reference strains. The three vaccines induced broadly comparable geometric mean fold-rises, post-vaccination geometric mean titers, proportions achieving titers >=40, and seroconversion rates against vaccine strains. These real-world data support the interchangeability of the three products for seasonal influenza vaccination programs among healthcare workers.",
  "abstract_shown": true,
  "affiliations": [
    "The University of Hong Kong"
  ],
  "article_type": "PUBLISHAHEADOFPRINT",
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "name": "W. W. Lim"
    },
    {
      "name": "L. Touyon"
    },
    {
      "name": "L. Mak"
    },
    {
      "name": "Y. C. Lau"
    },
    {
      "name": "S. M. S. Cheng"
    },
    {
      "name": "D. K. M. Ip"
    },
    {
      "name": "M. Peiris"
    },
    {
      "affs": [
        0
      ],
      "name": "B. J. Cowling"
    },
    {
      "name": "S.-S. Wong"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/bz820wgk3e6ej.bib",
  "cited_by": 0,
  "doi": "10.64898/2026.08.19.26360857",
  "fulltext_url": "https://www.medrxiv.org/content/10.64898/2026.08.19.26360857v2.full",
  "id": "bz820wgk3e6ej",
  "issns": [],
  "landing_url": "https://www.medrxiv.org/content/10.64898/2026.08.19.26360857v2",
  "language": null,
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "medrxiv",
      "infectious diseases"
    ],
    [
      "openalex",
      "2713|Influenza Virus Research Studies"
    ]
  ],
  "openalex": "W7204084422",
  "pdf_url": "https://www.medrxiv.org/content/10.64898/2026.08.19.26360857v2.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-08-19",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/bz820wgk3e6ej.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T00:20:43Z",
      "native_id": "10.64898/2026.08.19.26360857",
      "source": "medrxiv",
      "url": "https://www.medrxiv.org/content/10.64898/2026.08.19.26360857v2"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "medrxiv:infectious diseases",
      "subfield": "infectious-disease"
    }
  ],
  "title": "Comparative immunogenicity of several inactivated influenza vaccines among healthcare workers in Hong Kong",
  "title_text": "Comparative immunogenicity of several inactivated influenza vaccines among healthcare workers in Hong Kong",
  "type": "preprint",
  "updated_at": "2026-11-01T00:20:31Z",
  "url": "https://research.draconitic.com/paper/bz820wgk3e6ej",
  "venue": "medRxiv",
  "versions": []
}