{
  "abstract": "We conducted a retrospective, population-based laboratory surveillance study during May 2023–December 2025 in Alberta, Canada, to characterize adult invasive enterovirus and parechovirus infections and to identify groups at high risk for those infections. Of 15,621 samples tested, 162 (1.0%) were virus positive, of which 51 (31.5%) samples from 39 patients indicated invasive infections. Cerebrospinal fluid, blood, and cardiac tissue were the most frequent virus-positive specimens. The invasive enterovirus and parechovirus incidence rate was 0.37 cases/100,000 person-years; rates were higher in patients <50 versus >50 years of age (incidence rate ratio 8.2; p<0.001). The annual incidence rates were 0.20–0.56 cases/100,000 person-years; rates appeared higher in 2025 than in 2024 (incidence rate ratio 2.1; p = 0.11). Severe disseminated enterovirus infection occurred in 2 patients who received ocrelizumab. Continuous surveillance and ongoing optimization of enterovirus and parechovirus detection assays is essential for comprehensive public health tracking.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 11,
  "authors": [
    {
      "name": "Jamil N. Kanji"
    },
    {
      "name": "Hong Yuan Zhou"
    },
    {
      "name": "Nathan Zelyas"
    },
    {
      "name": "Kanti Pabbaraju"
    },
    {
      "name": "Anita Wong"
    },
    {
      "name": "Kara Gill"
    },
    {
      "name": "Tarah Lynch"
    },
    {
      "name": "Graham Tipples"
    },
    {
      "name": "Nabeela Nathoo"
    },
    {
      "name": "Dima Kabbani"
    },
    {
      "name": "Adil Adatia"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/c06sf4rb6r6c3.bib",
  "cited_by": 0,
  "doi": "10.3201/eid3211.260941",
  "fulltext_url": "https://wwwnc.cdc.gov/eid/article/32/11/26-0941_article",
  "id": "c06sf4rb6r6c3",
  "issns": [
    "1080-6040",
    "1080-6059"
  ],
  "landing_url": "https://doi.org/10.3201/eid3211.260941",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Research"
    ],
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      "lcc",
      "R"
    ],
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      "lcc",
      "RC109-216"
    ],
    [
      "openalex",
      "2705|Viral Infections and Immunology Research"
    ]
  ],
  "openalex": "W7221753280",
  "pdf_url": null,
  "pmcid": "PMC13715878",
  "pmid": "42909846",
  "published": "2026-10-30",
  "publisher": "Centers for Disease Control and Prevention",
  "ris": "https://research.draconitic.com/paper/c06sf4rb6r6c3.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:44:09Z",
      "native_id": "a6f949645414496486a074efd4a9d66c",
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      "url": "https://doi.org/10.3201/eid3211.260941"
    },
    {
      "first_seen": "2026-11-01T12:23:04Z",
      "native_id": "PMC13715878",
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      "url": "https://doi.org/10.3201/eid3211.260941"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2705|Viral Infections and Immunology Research",
      "subfield": "cardiovascular"
    }
  ],
  "title": "Invasive Enterovirus and Parechovirus Infections in Adults, Alberta, Canada, 2023–2025",
  "title_text": "Invasive Enterovirus and Parechovirus Infections in Adults, Alberta, Canada, 2023–2025",
  "type": "peer-reviewed",
  "updated_at": "2026-11-04T12:21:18Z",
  "url": "https://research.draconitic.com/paper/c06sf4rb6r6c3",
  "venue": "Emerging Infectious Diseases",
  "versions": []
}