{
  "abstract": "Objectives : To study the predictive and prognostic values of serum erythropoietin levels (sEPO) measured at diagnosis in lower‐risk myelodysplastic syndromes. Methods : We analyzed clinical associations and prognosis with sEPO in 672/1610 patients with at least one year of follow‐up data in the prospective EUMDS study. Results : sEPO levels increase with WHO subtypes associated with erythroid hypoplasia and poorer risk IPSS‐R scores. sEPO is an independent predictor of transfusion free survival and levels < 200 IU/L predict response to ESA. sEPO is not an independent predictor of overall survival. Conclusions : sEPO predicts transfusion free survival and response to ESA. Trial Registration : The EUMDS Registry (ClinicalTrials.gov: Identifier NCT00600860).",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 20,
  "authors": [
    {
      "name": "Dominic Culligan"
    },
    {
      "name": "Adele Taylor"
    },
    {
      "name": "Alexandra Smith"
    },
    {
      "name": "Catherine Cargo"
    },
    {
      "name": "Howard Oster"
    },
    {
      "name": "Argiris Symeonidis"
    },
    {
      "name": "Reinhard Stauder"
    },
    {
      "name": "Saskia Langemeijer"
    },
    {
      "name": "Luca Malcovati"
    },
    {
      "name": "Pierre Fenaux"
    },
    {
      "name": "Jaroslav Čermák"
    },
    {
      "name": "Eva Hellström-Lindberg"
    },
    {
      "name": "Juliet Mills"
    },
    {
      "name": "Ioannis Kotsianidis"
    },
    {
      "name": "Maud d'Aveni"
    },
    {
      "name": "Corine van Marrewijk"
    },
    {
      "name": "Marlijn Hoeks"
    },
    {
      "name": "Theo de Witte"
    },
    {
      "name": "David Bowen"
    },
    {
      "name": "Moshe Mittelman"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/c20xbnw2hmvg8.bib",
  "cited_by": 0,
  "doi": "10.1002/jha2.70366",
  "fulltext_url": null,
  "id": "c20xbnw2hmvg8",
  "issns": [
    "2688-6146"
  ],
  "landing_url": "https://hal.univ-lorraine.fr/hal-05787689v1",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.sdv"
    ],
    [
      "openalex",
      "2720|Erythropoietin and Anemia Treatment"
    ]
  ],
  "openalex": "W7171678198",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-07-29",
  "publisher": "Wiley",
  "ris": "https://research.draconitic.com/paper/c20xbnw2hmvg8.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:51Z",
      "native_id": "hal-05787689",
      "source": "hal",
      "url": "https://hal.univ-lorraine.fr/hal-05787689v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "hal:0.sdv",
      "subfield": "general"
    }
  ],
  "title": "The Predictive Value of Serum Erythropoietin Levels Measured at Diagnosis in Patients With Myelodysplastic Syndromes",
  "title_text": "The Predictive Value of Serum Erythropoietin Levels Measured at Diagnosis in Patients With Myelodysplastic Syndromes",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:51Z",
  "url": "https://research.draconitic.com/paper/c20xbnw2hmvg8",
  "venue": "eJHaem",
  "versions": []
}