{
  "abstract": "Objective: To examine the prevalence of thiamine deficiency and its potential risk factors in cancer outpatients.\n\nMethods: A cross-sectional study of cancer outpatients aged ≥20 years at a regional hospital in Kyoto, Japan (January–February 2022). Thiamine deficiency was defined as ≤23 ng/mL by liquid chromatography-tandem mass spectrometry (LC-MS/MS). Multivariable logistic regression was used to estimate ORs and 95% CIs for potential risk factors for thiamine deficiency.\n\nResults: A total of 106 patients were included in this study (mean age 68.3 years, 61% female). Of the 106 patients, 27 (25.5%) had low thiamine levels despite the absence of recognised deficiency symptoms. In multivariable logistic regression analysis, the adjusted OR was 4.05 (95% CI 0.88 to 18.60).\n\nConclusions: The prevalence of thiamine deficiency was 25.5% among cancer outpatients without recognised symptoms. An association between low dietary intake and thiamine deficiency was suggested, though further large-scale studies are needed to confirm risk factors and guide management strategies.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Medical Oncology and Palliative Care, Mitsubishi Kyoto Hospital, Kyoto, Japan",
    "Departments of Psycho-Oncology, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan",
    "Department of Supportive Care Medicine, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan",
    "Departments of Psycho-Oncology, Saitama Medical University International Medical Center, Hidaka, Japan",
    "Department of Clinical Epidemiology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan"
  ],
  "article_type": "brief report",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Akira Yoshioka",
      "orcid": "0000-0002-7622-9624"
    },
    {
      "affs": [
        1
      ],
      "name": "Mayumi Ishida",
      "orcid": "0000-0003-1388-1284"
    },
    {
      "affs": [
        2
      ],
      "name": "Nozomu Uchida",
      "orcid": "0000-0002-2357-9823"
    },
    {
      "affs": [
        3
      ],
      "name": "Hideki Onishi",
      "orcid": "0000-0003-2949-2734"
    },
    {
      "affs": [
        4
      ],
      "name": "Izumi Sato",
      "orcid": "0000-0003-2548-8391"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/c26v70a1j69a4.bib",
  "cited_by": 0,
  "doi": "10.1136/spcare-2026-006243",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13725641/",
  "id": "c26v70a1j69a4",
  "issns": [
    "2045-435X",
    "2045-4368"
  ],
  "landing_url": "https://doi.org/10.1136/spcare-2026-006243",
  "language": "en",
  "licence": "CC-BY-NC-4.0",
  "licence_label": "CC BY-NC 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Short Report"
    ],
    [
      "openalex",
      "2728|Alcoholism and Thiamine Deficiency"
    ]
  ],
  "openalex": "W7160843526",
  "pdf_url": null,
  "pmcid": "PMC13725641",
  "pmid": "42114974",
  "published": "2026-05-11",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/c26v70a1j69a4.ris",
  "sources": [
    {
      "first_seen": "2026-11-04T12:23:59Z",
      "native_id": "PMC13725641",
      "source": "pmc",
      "url": "https://doi.org/10.1136/spcare-2026-006243"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2728|Alcoholism and Thiamine Deficiency",
      "subfield": "neurology"
    }
  ],
  "title": "Thiamine deficiency in outpatients at a regional cancer centre in Japan: cross-sectional observational study",
  "title_text": "Thiamine deficiency in outpatients at a regional cancer centre in Japan: cross-sectional observational study",
  "type": "peer-reviewed",
  "updated_at": "2026-11-06T12:21:50Z",
  "url": "https://research.draconitic.com/paper/c26v70a1j69a4",
  "venue": "BMJ Supportive & Palliative Care",
  "versions": []
}