{
  "abstract": "Objectives\n\nHypothermic fibrillatory arrest (HFA) has been associated with increased stroke risk in minimally invasive mitral valve surgery, although selection bias may confound this association.Methods\n\nWe performed a single-center retrospective analysis of minimally invasive mitral valve surgeries (July 2011 to December 2024) stratified by myocardial protection strategy (HFA vs aortic crossclamping [ACC]), assessed using propensity-score matching and multivariable logistic regression.Results\n\nOf 1258 patients, 984 underwent HFA and 274 received ACC. The fibrillatory arrest group had more complex profiles and greater rates of previous myocardial infarction (14.2% vs 4.7%), previous cardiac surgery (12.8% vs 2.2%), and urgent/emergent status (18.8% vs 10.2% all P < .05). Despite these greater-risk profiles, postoperative stroke rates were comparable (3.1% vs 3.7%, P = .57). After propensity matching, stroke remained comparable (3.3% vs 3.7%), and fibrillatory arrest was not independently associated with increased stroke risk (odds ratio, 0.94; P = .91). In-hospital mortality was also comparable (HFA: 2.6% vs ACC: 1.5%).Conclusions\n\nHFA demonstrated noninferior stroke outcomes compared with ACC when performed with meticulous protocols at high-volume centers. These findings do not support HFA as a replacement for ACC but rather as a viable alternative when clinically and technically indicated.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tenn.",
    "Vanderbilt University School of Medicine, Nashville, Tenn."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 13,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Awab Ahmad"
    },
    {
      "affs": [
        1
      ],
      "name": "Christian Eidson"
    },
    {
      "affs": [
        1
      ],
      "name": "Walter Navid"
    },
    {
      "affs": [
        1
      ],
      "name": "Emma Stimpfl"
    },
    {
      "affs": [
        1
      ],
      "name": "Chen Chia Wang"
    },
    {
      "affs": [
        1
      ],
      "name": "Mark Petrovic"
    },
    {
      "affs": [
        0
      ],
      "name": "Aaron M Williams"
    },
    {
      "affs": [
        0
      ],
      "name": "John Trahanas"
    },
    {
      "affs": [
        0
      ],
      "name": "Swaroop Bommareddi"
    },
    {
      "affs": [
        0
      ],
      "name": "Eric Quintana"
    },
    {
      "affs": [
        0
      ],
      "name": "Brian Lima"
    },
    {
      "affs": [
        0
      ],
      "name": "Ashish S Shah"
    },
    {
      "affs": [
        0
      ],
      "name": "Tarek Absi"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/c3ag5crdz460z.bib",
  "cited_by": 0,
  "doi": "10.1016/j.xjon.2026.102054",
  "fulltext_url": "https://europepmc.org/articles/PMC13711216",
  "id": "c3ag5crdz460z",
  "issns": [
    "2666-2736"
  ],
  "landing_url": "https://europepmc.org/article/MED/42948508",
  "language": "eng",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Adult: Mitral Valve"
    ],
    [
      "openalex",
      "2705|Cardiac Valve Diseases and Treatments"
    ]
  ],
  "openalex": "W7203965533",
  "pdf_url": "https://europepmc.org/articles/PMC13711216?pdf=render",
  "pmcid": "PMC13711216",
  "pmid": "42948508",
  "published": "2026-08-22",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/c3ag5crdz460z.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T00:20:35Z",
      "native_id": "MED:42948508",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42948508"
    },
    {
      "first_seen": "2026-10-31T12:22:02Z",
      "native_id": "PMC13711216",
      "source": "pmc",
      "url": "https://doi.org/10.1016/j.xjon.2026.102054"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2705|Cardiac Valve Diseases and Treatments",
      "subfield": "cardiovascular"
    }
  ],
  "title": "Hypothermic fibrillatory arrest may not increase stroke risk in minimally invasive mitral valve surgery: A 13-year propensity score-matched experience.",
  "title_text": "Hypothermic fibrillatory arrest may not increase stroke risk in minimally invasive mitral valve surgery: A 13-year propensity score-matched experience.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-31T12:22:02Z",
  "url": "https://research.draconitic.com/paper/c3ag5crdz460z",
  "venue": "JTCVS open",
  "versions": []
}