{
  "abstract": "Alzheimer's disease (AD) is a neurodegenerative disorder. Irreversible pathological alterations are already present when clinical symptoms emerge. Therefore, early diagnosis and intervention are crucial for improving patient outcomes and reducing the social and healthcare burden. With its advantages of minimal invasiveness, convenience, affordability, and high accessibility, blood-based testing has overcome the limitations of conventional methods, becoming a major focus of research in early AD diagnosis in recent years. Based on the key domestic and international research findings in recent years, this paper systematically reviews the types, mechanisms of action, and relevant detection technologies of blood-based biomarkers for AD.",
  "abstract_shown": true,
  "affiliations": [
    "School of International Medical Technology Shanghai Sanda University Shanghai China.",
    "Department of Gerontology Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai China."
  ],
  "article_type": "review article",
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Shuangshuang Li"
    },
    {
      "affs": [
        1
      ],
      "name": "Lin Huang"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Qihao Guo",
      "orcid": "0000-0001-5079-8047"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/c492gxcnfkjwy.bib",
  "cited_by": 0,
  "doi": "10.1002/agm2.70112",
  "fulltext_url": "https://europepmc.org/articles/PMC13713016",
  "id": "c492gxcnfkjwy",
  "issns": [
    "2475-0360"
  ],
  "landing_url": "https://europepmc.org/article/MED/42948835",
  "language": "eng",
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Review Article"
    ],
    [
      "openalex",
      "2738|Dementia and Cognitive Impairment Research"
    ]
  ],
  "openalex": "W7223956118",
  "pdf_url": "https://europepmc.org/articles/PMC13713016?pdf=render",
  "pmcid": "PMC13713016",
  "pmid": "42948835",
  "published": "2026-10-27",
  "publisher": "Wiley",
  "ris": "https://research.draconitic.com/paper/c492gxcnfkjwy.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T00:20:33Z",
      "native_id": "MED:42948835",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42948835"
    },
    {
      "first_seen": "2026-10-31T12:23:29Z",
      "native_id": "PMC13713016",
      "source": "pmc",
      "url": "https://doi.org/10.1002/agm2.70112"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2738|Dementia and Cognitive Impairment Research",
      "subfield": "psychiatry"
    }
  ],
  "title": "Blood-Based Biomarkers in Alzheimer's Disease: Advances in Detection Technologies and Clinical Applications.",
  "title_text": "Blood-Based Biomarkers in Alzheimer's Disease: Advances in Detection Technologies and Clinical Applications.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-31T12:23:29Z",
  "url": "https://research.draconitic.com/paper/c492gxcnfkjwy",
  "venue": "Aging medicine (Milton (N.S.W))",
  "versions": []
}