{
  "abstract": "Background: Multidisciplinary team (MDT) strategies and geriatric assessment (GA) are widely used in cancer treatment to guide more individualized treatment recommendations and improve prognosis.\n\nMethods: In this retrospective analysis of a prospectively collected observational cohort, we evaluated the association of GA parameters with MDT treatment recommendations and with patient concordance with those recommendations in older patients with breast cancer. A total of 211 patients aged ≥60 years were enrolled. GA was assessed using nine instruments before surgery, and adjuvant treatment decisions were made by MDT discussions. Associations between GA parameters and MDT treatment recommendations, and concordance with those recommendations, were analyzed.\n\nResults: Patients with lower Vulnerable Elders Survey (VES-13) scores (better status) (95.7% vs. 77.8%, p = 0.021) and higher Barthel Index (BI) scores (better status) (96.7% vs. 75%, p = 0.003) were more frequently recommended adjuvant radiotherapy. The rate of adjuvant chemotherapy recommendation was also higher for patients with lower VES-13 scores (46.8% vs. 21.1%, p = 0.004) and higher BI scores (45.6% vs. 27.5%, p = 0.037). Concordance with the recommended adjuvant chemotherapy was higher among patients with lower modified Charlson Comorbidity Index (CCI) scores (better status; CCI without age points) (80.3% vs. 53.8%, p = 0.038).\n\nConclusion: These findings indicate that GA parameters were associated with MDT treatment recommendations and with concordance with recommended adjuvant chemotherapy in older patients with breast cancer.",
  "abstract_shown": true,
  "affiliations": [
    "Department of General Surgery, Comprehensive Breast Health Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Yihua Jin"
    },
    {
      "affs": [
        0
      ],
      "name": "Jing Yu"
    },
    {
      "affs": [
        0
      ],
      "name": "Xu Zhang"
    },
    {
      "affs": [
        0
      ],
      "name": "Siji Zhu"
    },
    {
      "affs": [
        0
      ],
      "name": "Kunwei Shen"
    },
    {
      "affs": [
        0
      ],
      "name": "Xiaosong Chen"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/c62xwvqst67ar.bib",
  "cited_by": 0,
  "doi": "10.3389/fonc.2026.1892469",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13727386/?tool=EBI",
  "id": "c62xwvqst67ar",
  "issns": [
    "2234-943X"
  ],
  "landing_url": "https://www.frontiersin.org/articles/10.3389/fonc.2026.1892469/full",
  "language": "eng",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Original Research"
    ],
    [
      "openalex",
      "2717|Frailty in Older Adults"
    ]
  ],
  "openalex": "W7223008135",
  "pdf_url": "https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2026.1892469/pdf",
  "pmcid": "PMC13727386",
  "pmid": "42974403",
  "published": "2026-10-20",
  "publisher": "Frontiers Media SA",
  "ris": "https://research.draconitic.com/paper/c62xwvqst67ar.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:20:13Z",
      "native_id": "10.3389/fonc.2026.1892469",
      "source": "crossref",
      "url": "https://www.frontiersin.org/articles/10.3389/fonc.2026.1892469/full"
    },
    {
      "first_seen": "2026-11-03T15:20:51Z",
      "native_id": "PMC:PMC13727386",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13727386"
    },
    {
      "first_seen": "2026-11-04T15:20:48Z",
      "native_id": "MED:42974403",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42974403"
    },
    {
      "first_seen": "2026-11-05T12:23:28Z",
      "native_id": "PMC13727386",
      "source": "pmc",
      "url": "https://doi.org/10.3389/fonc.2026.1892469"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "issn:2234-943X",
      "subfield": "oncology"
    }
  ],
  "title": "Association of geriatric assessment with multidisciplinary treatment recommendations and treatment concordance among older patients with breast cancer",
  "title_text": "Association of geriatric assessment with multidisciplinary treatment recommendations and treatment concordance among older patients with breast cancer",
  "type": "peer-reviewed",
  "updated_at": "2026-11-06T12:23:04Z",
  "url": "https://research.draconitic.com/paper/c62xwvqst67ar",
  "venue": "Frontiers in Oncology",
  "versions": []
}