{
  "abstract": "Objectives\n\nTo evaluate the safety, visual outcomes, and complication profile of femtosecond laser-assisted cataract surgery (FLACS) combined with 25-gauge pars plana vitrectomy (PPV) in patients with concurrent cataract and vitreoretinal disease.Methods\n\nThis retrospective study included 57 eyes of 57 patients who underwent FLACS with a standardized 4.8-mm capsulotomy followed by 25-gauge PPV at a tertiary referral center in Istanbul, Turkey, between August 2020 and May 2025. Data collected included intraoperative events, postoperative best-corrected visual acuity (BCVA, Snellen converted to logMAR for analysis), intraocular pressure (IOP), and complication rates over a mean follow-up of 15.8±1.8 months.Results\n\nMean BCVA significantly improved from 0.68±0.34 logMAR preoperatively to 0.28±0.14 logMAR at 1 month, 0.19±0.11 logMAR at 3 months, and 0.15±0.14 logMAR at the final visit (all p<0.001). All eyes achieved meaningful visual recovery with stable and well-centered intraocular lenses and attached retinas. On postoperative day 1, post-hoc pairwise analysis revealed a significantly lower IOP in the air tamponade group compared with the SF6 and BSS groups (MD=-4.24, p<0.001); no significant IOP differences were found between groups at week 1, month 1, or month 3. Intraoperative complications included loss of cone suction (n=2, 3.5%) and incomplete capsulorhexis (n=2, 3.5%). Miosis occurred in 6 eyes (10.5%), and sclerotomy leakage requiring suturing in 7 eyes (12.3%).Conclusions\n\nCombined FLACS and 25-gauge PPV is a safe and effective option for the management of coexisting cataract and vitreoretinal pathologies. The procedure provides favorable anatomical and visual outcomes with a low incidence of intraoperative and postoperative complications, supporting its use in appropriately selected patients. Prospective controlled studies are warranted to confirm these findings.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Vitreoretinal Surgery, Dunyagoz Eye Hospital, Istanbul, Türkiye.",
    "Department of Ophthalmology, Bezmialem Vakif University, Faculty of Medicine, Istanbul, Türkiye."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 2,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Fevzi Akkan"
    },
    {
      "affs": [
        1
      ],
      "name": "Ersin Akbulut"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/c6tje5rj6vnpt.bib",
  "cited_by": 0,
  "doi": "10.14744/bej.2026.38802",
  "fulltext_url": "https://europepmc.org/articles/PMC13678147",
  "id": "c6tje5rj6vnpt",
  "issns": [
    "2459-1777",
    "2587-0394"
  ],
  "landing_url": "https://europepmc.org/article/MED/42898541",
  "language": "eng",
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2741|Retinal and Macular Surgery"
    ]
  ],
  "openalex": "W7215127141",
  "pdf_url": "https://europepmc.org/articles/PMC13678147?pdf=render",
  "pmcid": "PMC13678147",
  "pmid": "42898541",
  "published": "2026-10-01",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/c6tje5rj6vnpt.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:37Z",
      "native_id": "MED:42898541",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42898541"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2741|Retinal and Macular Surgery",
      "subfield": "imaging"
    }
  ],
  "title": "Outcomes and Safety of Femtosecond Laser-Assisted Phacovitrectomy Using 25-Gauge Pars Plana Vitrectomy.",
  "title_text": "Outcomes and Safety of Femtosecond Laser-Assisted Phacovitrectomy Using 25-Gauge Pars Plana Vitrectomy.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:19:37Z",
  "url": "https://research.draconitic.com/paper/c6tje5rj6vnpt",
  "venue": "Beyoglu eye journal",
  "versions": []
}