{
  "abstract": "Breast cancer among Chinese women aged 25-49 years has substantial clinical and societal consequences. We integrated Global Burden of Disease (GBD) 2023 estimates for 1990-2023 with Global Cancer Observatory (GLOBOCAN) 2022, United Nations population projections, International Labour Organization labour-force participation, and World Bank indicators. Incident cases rose from 50,064 to 87,221, while the weighted death rate declined from 9.25 to 4.72 per 100,000. Demographic changes explained 63.0% of additional cases. In exploratory extreme gradient boosting (XGBoost) analyses interpreted with SHapley Additive exPlanations (SHAP), the fasting-plasma-glucose-related population attributable fraction (PAF) ranked first in several formulations but weakened after removing age and temporal structure; the selected high-body-mass-index (BMI) PAF series was constant at zero and unrankable. Potential mortality-related productivity loss was US$6.161 billion in 2023. Status-quo projections suggested increasing incidence through 2050 with very wide uncertainty, supporting surveillance and individual-level validation rather than immediate screening policy changes.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": "Article",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "name": "Yang Bai",
      "orcid": "0009-0001-4478-4383"
    },
    {
      "name": "Jiaqi Zhang",
      "orcid": "0009-0005-8604-5940"
    },
    {
      "name": "Tian Tian",
      "orcid": "0009-0003-8383-3867"
    },
    {
      "name": "Ke Wang"
    },
    {
      "name": "Jian Zhang",
      "orcid": "0000-0003-1144-3627"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/c7j75qqwz8wng.bib",
  "cited_by": 0,
  "doi": "10.1016/j.isci.2026.117891",
  "fulltext_url": "https://europepmc.org/articles/PMC13683865",
  "id": "c7j75qqwz8wng",
  "issns": [
    "2589-0042"
  ],
  "landing_url": "https://www.cell.com/iscience/fulltext/S2589-0042(26)03274-8",
  "language": "eng",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "http://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Health sciences"
    ],
    [
      "heading",
      "Medical specialty"
    ],
    [
      "heading",
      "Medicine"
    ],
    [
      "heading",
      "Oncology"
    ],
    [
      "heading",
      "Public health"
    ],
    [
      "openalex",
      "2730|Global Cancer Incidence and Screening"
    ]
  ],
  "openalex": "W7221764173",
  "pdf_url": "https://europepmc.org/articles/PMC13683865?pdf=render",
  "pmcid": "PMC13683865",
  "pmid": "42909293",
  "published": "2026-10-14",
  "publisher": "Elsevier BV",
  "ris": "https://research.draconitic.com/paper/c7j75qqwz8wng.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:16Z",
      "native_id": "10.1016/j.isci.2026.117891",
      "source": "feed-cell",
      "url": "https://www.cell.com/iscience/fulltext/S2589-0042(26)03274-8"
    },
    {
      "first_seen": "2026-10-30T12:17:49Z",
      "native_id": "10.1016/j.isci.2026.117891",
      "source": "crossref",
      "url": "https://linkinghub.elsevier.com/retrieve/pii/S2589004226032748"
    },
    {
      "first_seen": "2026-10-30T12:20:10Z",
      "native_id": "MED:42909293",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42909293"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "heading:Public health",
      "subfield": "epidemiology-public-health"
    },
    {
      "field": "medicine",
      "origin": "heading:Oncology",
      "subfield": "oncology"
    }
  ],
  "title": "Breast cancer burden risk attribution and productivity loss in Chinese women aged 25 to 49",
  "title_text": "Breast cancer burden risk attribution and productivity loss in Chinese women aged 25 to 49",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:20:10Z",
  "url": "https://research.draconitic.com/paper/c7j75qqwz8wng",
  "venue": "iScience",
  "versions": []
}