{
  "abstract": "IgA nephropathy (IgAN) is a major cause of chronic kidney disease in South Asia, particularly among young adults. Although recent therapeutic advances have transformed IgAN management globally, access to these treatments in South Asia remains limited. Most patients continue to rely on supportive care and conventional immunosuppressives, which have limited efficacy and significant adverse effects. Multiple barriers hinder implementation of newer therapies, including shortage of healthcare capacity and specialist nephrology care leading to delayed diagnosis, high treatment costs, limited resources, lack of universal health coverage, regulatory challenges, and underrepresentation of South Asian populations in clinical trials. This viewpoint discusses the current landscape of IgAN management in South Asia and outlines strategies to improve equitable access to novel therapies, including strengthening healthcare infrastructure and workforce, expanding screening and diagnostic capacity, implementing pricing and reimbursement reforms, facilitating clinical trials and local evidence generation, improving disease awareness in the community as well as healthcare professionals, and enhancing stakeholder advocacy and policy engagement.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Nephrology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India",
    "Department of Nephrology, Medanta Kidney and Urology Institute, Medanta Hospital, Gurugram, Haryana, India",
    "Faculty of Medicine, Department of Clinical Medicine, University of Colombo, Colombo, Sri Lanka",
    "Consultant, Kidney Centre, Green Life Medical College & Hospital, Dhaka, Bangladesh",
    "Department of Nephrology and Transplantation Medicine, Tribhuvan University Teaching Hospital, Institute of Medicine, Kathmandu, Nepal",
    "Department of Nephrology, All India Institute of Medical Sciences, New Delhi, India",
    "Centre for Kidney Research, Westmead Hospital, Sydney, Australia",
    "Sydney School of Public Health, Australia"
  ],
  "article_type": "review article",
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Sana Shadab"
    },
    {
      "affs": [
        1
      ],
      "name": "Shyam Bihari Bansal"
    },
    {
      "affs": [
        2
      ],
      "name": "Eranga Wijewickrama"
    },
    {
      "affs": [
        3
      ],
      "name": "Muhammad Rafiqul Alam"
    },
    {
      "affs": [
        4
      ],
      "name": "Dibya Singh Shah"
    },
    {
      "affs": [
        5,
        6,
        7
      ],
      "name": "Soumita Bagchi"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/c7s4qb6746a76.bib",
  "cited_by": 0,
  "doi": "10.1016/j.lansea.2026.100812",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13697813/",
  "id": "c7s4qb6746a76",
  "issns": [
    "2772-3682"
  ],
  "landing_url": "https://doi.org/10.1016/j.lansea.2026.100812",
  "language": "en",
  "licence": "CC-BY-NC-ND-4.0",
  "licence_label": "CC BY-NC-ND 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Viewpoint"
    ],
    [
      "openalex",
      "2727|Renal Diseases and Glomerulopathies"
    ]
  ],
  "openalex": "W7170090156",
  "pdf_url": "https://europepmc.org/articles/PMC13697813?pdf=render",
  "pmcid": "PMC13697813",
  "pmid": "42935959",
  "published": "2026-07-22",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/c7s4qb6746a76.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:18:48Z",
      "native_id": "PMC13697813",
      "source": "pmc",
      "url": "https://doi.org/10.1016/j.lansea.2026.100812"
    },
    {
      "first_seen": "2026-10-30T12:22:24Z",
      "native_id": "MED:42935959",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42935959"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2727|Renal Diseases and Glomerulopathies",
      "subfield": "general"
    }
  ],
  "title": "Challenges in access to novel IgA nephropathy therapeutics in South Asia",
  "title_text": "Challenges in access to novel IgA nephropathy therapeutics in South Asia",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:34:47Z",
  "url": "https://research.draconitic.com/paper/c7s4qb6746a76",
  "venue": "The Lancet Regional Health - Southeast Asia",
  "versions": []
}