{
  "abstract": "Rosa roxburghii ( RRT ) is a nutritionally and medicinally important Rosaceae species that accumulates diverse bioactive compounds, making it an excellent system for investigating the genetic basis and evolutionary diversification of specialized metabolism. Here, we report a complete telomere-to-telomere (T2T), gap-free genome assembly of the elite cultivar ‘Guinong No. 5’ ( RRT5 ), comprising 494.57 Mb with a contig N50 of 51.44 Mb and a base accuracy of over 99.99%. Of this assembly, 99.9% were anchored to seven pseudo-chromosomes. Multi-omics analyses identified OSC , CYP , and UGT genes potentially involved in triterpenoid biosynthesis, while gene–metabolite correlation analyses highlighted MYB30 and MYB31 as candidate regulators of multiple triterpenoids. Notably, the biosynthetic capacities for Kaji-ichigoside F1 and rosamultin vary across lineages within Rosoideae, likely reflecting lineage-specific gene gain or loss and/or evolutionary divergence in regulatory pathways. Together, the RRT5 genome, transcriptome, and profiling of the eight key triterpenoids provide a valuable resource for elucidating triterpenoid biosynthesis, regulation, and evolution, and for guiding genome-informed breeding of R. roxburghii .",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 8,
  "authors": [
    {
      "name": "Liangqun Li"
    },
    {
      "name": "Mei Peng"
    },
    {
      "name": "Yanfang Yan"
    },
    {
      "name": "Qun Chen"
    },
    {
      "name": "Hong Liao",
      "orcid": "0000-0001-8563-7374"
    },
    {
      "name": "Juan Yang"
    },
    {
      "name": "Xiaosheng Yang"
    },
    {
      "name": "Xiaojun Pu",
      "orcid": "0000-0001-9604-1226"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/c88k0ny8b6435.bib",
  "cited_by": 0,
  "doi": "10.1038/s42003-026-11106-x",
  "fulltext_url": null,
  "id": "c88k0ny8b6435",
  "issns": [
    "2399-3642"
  ],
  "landing_url": "https://www.nature.com/articles/s42003-026-11106-x",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1312|Plant biochemistry and biosynthesis"
    ]
  ],
  "openalex": "W7221079731",
  "pdf_url": "https://www.nature.com/articles/s42003-026-11106-x_reference.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-09",
  "publisher": "Springer Science and Business Media LLC",
  "ris": "https://research.draconitic.com/paper/c88k0ny8b6435.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:50Z",
      "native_id": "10.1038/s42003-026-11106-x",
      "source": "crossref",
      "url": "https://www.nature.com/articles/s42003-026-11106-x"
    }
  ],
  "subjects": [
    {
      "field": "biochemistry",
      "origin": "openalex:1312|Plant biochemistry and biosynthesis",
      "subfield": "molecular-biology"
    }
  ],
  "title": "A telomere-to-telomere reference genome for Rosa roxburghii reveals lineage-specific diversification of triterpenoid biosynthesis",
  "title_text": "A telomere-to-telomere reference genome for Rosa roxburghii reveals lineage-specific diversification of triterpenoid biosynthesis",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:50Z",
  "url": "https://research.draconitic.com/paper/c88k0ny8b6435",
  "venue": "Communications Biology",
  "versions": []
}