{
  "abstract": "Background The efficacy of Impella in ischemic cardiogenic shock (CS) has been examined. This study evaluated the Impella clinical course in non-ischemic CS and examined the differences in 72-h factors after Impella implantation between successful and unsuccessful weaning. Methods This observational, retrospective, single-center cohort study included 43 patients with non-ischemic CS [fulminant myocarditis (n=25) and HF-related CS (n=18)] from July 2018 to July 2022. The background, clinical course, and clinical predictors of successful weaning were evaluated in this study. Results The median age was 45 (31-53) years; 37% (n=16) were women, 79% (n=34) were on concomitant veno-arterial extracorporeal membrane oxygenation. duration of Impella use was 11 (6-20) days; 14% (n=6) had severe bleeding, 26% (n=11) had bacteremia complications, and 53% (n=24) required new temporary dialysis. The 30-day unsuccessful Impella weaning rates for HF-related CS and fulminant myocarditis were 36% and 33%; the 365-day rates were 48% and 67%, respectively. Regarding the factors between successful and unsuccessful Impella weaning, left ventricular ejection fraction and serum lactate dehydrogenase levels significantly differed 72 h after Impella implantation in fulminant myocarditis and with systolic blood pressure in HF-related CS. Conclusion In non-ischemic CS cases requiring Impella, successful weaning rates vary greatly depending on the underlying disease, and the factor at 72h after Impella insertion are associated with the subsequent course.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 13,
  "authors": [
    {
      "name": "Yuichiro Koyama"
    },
    {
      "name": "Ryota Morimoto"
    },
    {
      "name": "Shin Nagai"
    },
    {
      "name": "Asuka Nozaki"
    },
    {
      "name": "Chiaki Mizuno"
    },
    {
      "name": "Ryota Ito"
    },
    {
      "name": "Kiyota Kondo"
    },
    {
      "name": "Shotaro Komeyama"
    },
    {
      "name": "Yusuke Fujikawa"
    },
    {
      "name": "Shingo Kazama"
    },
    {
      "name": "Hiroaki Hiraiwa"
    },
    {
      "name": "Toru Kondo"
    },
    {
      "name": "Toyoaki Murohara"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/c9b9nj1j9n4yz.bib",
  "cited_by": 0,
  "doi": "10.2169/internalmedicine.7329-26",
  "fulltext_url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7329-26/_article",
  "id": "c9b9nj1j9n4yz",
  "issns": [
    "1349-7235",
    "0918-2918"
  ],
  "landing_url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7329-26/_article",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "jstage-journal",
      "medicine/general"
    ],
    [
      "openalex",
      "2204|Mechanical Circulatory Support Devices"
    ]
  ],
  "openalex": "W7170823318",
  "pdf_url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7329-26/_pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-07-25",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/c9b9nj1j9n4yz.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:31Z",
      "native_id": "10.2169/internalmedicine.7329-26",
      "source": "jstage",
      "url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7329-26/_article"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "jstage-journal:medicine/general",
      "subfield": "general"
    }
  ],
  "title": "Clinical Associations of Successful Weaning from Impella Support in Non-ischemic Cardiogenic Shock",
  "title_text": "Clinical Associations of Successful Weaning from Impella Support in Non-ischemic Cardiogenic Shock",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:31Z",
  "url": "https://research.draconitic.com/paper/c9b9nj1j9n4yz",
  "venue": "Internal Medicine",
  "versions": []
}