{
  "abstract": "Purpose: To compare recurrence after conjunctival autograft (CAG) and amniotic membrane transplantation (AMT) for primary pterygium and to identify unadjusted predictors of recurrence, with an exploratory analysis by age group.\n\nPatients and Methods: This retrospective cohort study included 402 patients who underwent primary pterygium excision by a single surgeon over 10 years (CAG, n=193; AMT, n=209). Patients chose their surgical technique after counselling, and all were followed for 12 months. The primary outcome was recurrence, defined as fibrovascular tissue extending ≥1.5 mm onto the cornea. Associations were assessed with chi-square or Fisher’s exact tests. All analyses were unadjusted; multivariable regression was not performed because of the limited number of recurrence events. Recurrence-free probability was estimated with the Kaplan–Meier method and compared with the log-rank test. Effect sizes were reported as odds ratio (OR), absolute risk reduction (ARR), relative risk reduction (RRR), and number needed to treat (NNT). Age-stratified analyses were exploratory.\n\nResults: The overall recurrence rate was 11.7% (47/402) at 12 months, and all recurrences occurred within 9 months. Recurrence was lower with CAG than AMT (8.3% vs 14.8%; Fisher’s exact p=0.044), with an unadjusted OR for AMT of 1.93 (95% CI: 1.02–3.65), ARR of 6.5% points, RRR of 44.1%, and NNT of 15.3. Recurrence-free probability at 12 months was 91.7% with CAG and 85.2% with AMT (log-rank p=0.041). In exploratory age-stratified analyses, recurrence was 0% (0/54) with CAG vs 21.1% (15/71) with AMT in patients aged 20–40 years, with no difference in patients aged 41–60 years (11.1% vs 11.5%); the group aged >60 years (n=12) was too small to interpret. No other variable was associated with recurrence in unadjusted analyses.\n\nConclusion: In this non-randomized cohort, in which patients chose their technique, CAG was associated with lower recurrence than AMT. The apparent difference in younger patients is hypothesis-generating only and requires prospective confirmation, and residual confounding, including by pterygium grade, cannot be excluded.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Ophthalmology, Faculty of Medicine, Burapha University, Chonburi, Thailand",
    "Burapha University Hospital, Burapha University, Chonburi, Thailand"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 2,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Luksanaporn Krungkraipetch",
      "orcid": "0000-0003-0806-8264"
    },
    {
      "affs": [
        1
      ],
      "name": "Warisanan Puranawit"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/c9xsd7bjpng7h.bib",
  "cited_by": 0,
  "doi": "10.2147/opth.s648867",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13738232/",
  "id": "c9xsd7bjpng7h",
  "issns": [
    "1177-5467",
    "1177-5483"
  ],
  "landing_url": "https://doi.org/10.2147/opth.s648867",
  "language": "en",
  "licence": "CC-BY-NC-4.0",
  "licence_label": "CC BY-NC 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Original Research"
    ],
    [
      "openalex",
      "2731|Corneal Surgery and Treatments"
    ]
  ],
  "openalex": "W7225014481",
  "pdf_url": "https://www.dovepress.com/article/download/121664",
  "pmcid": "PMC13738232",
  "pmid": "42992175",
  "published": "2026-11-01",
  "publisher": "Dove Press",
  "ris": "https://research.draconitic.com/paper/c9xsd7bjpng7h.ris",
  "sources": [
    {
      "first_seen": "2026-11-09T12:23:15Z",
      "native_id": "PMC13738232",
      "source": "pmc",
      "url": "https://doi.org/10.2147/opth.s648867"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2731|Corneal Surgery and Treatments",
      "subfield": "general"
    }
  ],
  "title": "Recurrence After Conjunctival Autograft versus Amniotic Membrane Transplantation for Primary Pterygium: A Retrospective Kaplan-Meier Cohort Study",
  "title_text": "Recurrence After Conjunctival Autograft versus Amniotic Membrane Transplantation for Primary Pterygium: A Retrospective Kaplan-Meier Cohort Study",
  "type": "peer-reviewed",
  "updated_at": "2026-11-09T12:23:15Z",
  "url": "https://research.draconitic.com/paper/c9xsd7bjpng7h",
  "venue": "Clinical Ophthalmology (Auckland, N.Z.)",
  "versions": []
}