{
  "abstract": "A break-junction experiment records thousands of single-molecule junctions in one session and reports a feature of their conductance histogram as the molecule’s conductance, with an uncertainty from resampling the traces. That is a withinsession sampling figure; how far the value moves between sessions is not measured or budgeted. We measure it in ISO 5725 and GUM form on archived STM-BJ recordings of DNA:RNA hybrid duplexes with repeat sessions at identical settings. On seven single-duplex groups, each two sessions from different recording rounds or dates, the intermediate-precision standard deviation of a session’s median is a factor of 1.46 (95% interval 1.28 to 2.15). Read in recording order, the median also wanders within a session with a correlation length near a hundred traces, so resampling understates the within-session uncertainty about threefold; counted consistently, the between-session term holds 74% of a single-session variance budget, and on records of this length it cannot be separated from slow drift. Five candidate remedies, tested under pre-registration, do not remove it. The expanded uncertainty of a single-session value, a lower bound that excludes calibration terms, is a factor of 2.4; spreading a fixed number of traces over more sessions reduces it, and a design rule gives the sessions a comparison needs. Public deposits from a second laboratory show a between-occasion component and the same within-session dependence. The figures are specific to the system; the method is not.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 1,
  "authors": [
    {
      "name": "Viraaj Minhas",
      "orcid": "0009-0007-4751-3945"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/ca3jand1ah8qb.bib",
  "cited_by": 0,
  "doi": "10.26434/chemrxiv.15010359/v1",
  "fulltext_url": null,
  "id": "ca3jand1ah8qb",
  "issns": [],
  "landing_url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15010359/v1",
  "language": null,
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2208|Molecular Junctions and Nanostructures"
    ]
  ],
  "openalex": "W7221621790",
  "pdf_url": "https://chemrxiv.org/doi/pdf/10.26434/chemrxiv.15010359/v1",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-13",
  "publisher": "American Chemical Society (ACS)",
  "ris": "https://research.draconitic.com/paper/ca3jand1ah8qb.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:24Z",
      "native_id": "10.26434/chemrxiv.15010359",
      "source": "chemrxiv",
      "url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15010359/v1"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "source:chemrxiv",
      "subfield": "general"
    }
  ],
  "title": "Intermediate Precision of Single-Molecule Break-Junction Conductance: Measurement, Uncertainty Budget, and Design Rules",
  "title_text": "Intermediate Precision of Single-Molecule Break-Junction Conductance: Measurement, Uncertainty Budget, and Design Rules",
  "type": "preprint",
  "updated_at": "2026-10-30T12:17:24Z",
  "url": "https://research.draconitic.com/paper/ca3jand1ah8qb",
  "venue": "ChemRxiv",
  "versions": []
}