{
  "abstract": "This study aimed to evaluate the effects of dietary supplementation with probiotics (PRO), synbiotics (SYN), and SYN + benzoic acid (SYP) on growth performance, stress response, nutrient digestibility, blood parameters, immune status, and intestinal health of weanling pigs. Four hundred weaned pigs (Landrace × Yorkshire × Duroc) were allocated to four treatment groups: control (basal diet), PRO (Bacillus licheniformis), SYN (Bacillus licheniformis + dietary fiber), and SYP. The feeding trial lasted for 28 days. Notably, pigs in the SYN and SYP groups showed greater average daily gain during phase 1 (p = 0.038), phase 2 (p = 0.008), and the overall period (p = 0.011) compared with those in the control group. Gain-to-feed ratio was also improved during phase 2 (p = 0.003) and the overall experimental period (p = 0.012). The SYP group demonstrated significantly improved dry matter digestibility during phase 2 (p < 0.05). Serum IL-1β concentrations tended to decrease in pigs fed SYN and SYP diets. In addition, SYN and SYP supplementation increased the concentration of the tight junction protein zona occludens-1 (ZO-1) in the jejunum (p = 0.022). Histological analysis showed greater villus height in the duodenum (p = 0.013) and jejunum (p = 0.038) of pigs fed SYN and SYP diets. Overall, dietary supplementation with synbiotics, particularly in combination with benzoic acid, improved growth performance and intestinal health in weanling pigs.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Livestock, Korea National University of Agriculture and Fisheries, Jeonju, Korea.",
    "Department of Research and Development, Center for Industrialization of Agricultural and Livestock Microorganisms, Jeongeup, Korea.",
    "Woogene B&G Co., Ltd., Hwaseong, Korea."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Su Hyup Lee",
      "orcid": "0000-0001-8996-3740"
    },
    {
      "affs": [
        1
      ],
      "name": "Sunbong Choi",
      "orcid": "0009-0004-1257-1588"
    },
    {
      "affs": [
        2
      ],
      "name": "Young Bin Park",
      "orcid": "0000-0002-2342-7475"
    },
    {
      "affs": [
        1
      ],
      "name": "Hyun-Jun Jang",
      "orcid": "0000-0003-2906-7543"
    },
    {
      "affs": [
        1
      ],
      "name": "Soyeon Park",
      "orcid": "0000-0003-3788-5415"
    },
    {
      "affs": [
        1
      ],
      "name": "Yangseon Kim",
      "orcid": "0000-0002-8285-3407"
    },
    {
      "affs": [
        0
      ],
      "name": "Jin-Ki Park",
      "orcid": "0000-0002-8423-5848"
    },
    {
      "affs": [
        2
      ],
      "name": "Sung Ho Lee",
      "orcid": "0009-0001-5753-3516"
    },
    {
      "affs": [
        0
      ],
      "name": "Dong Wook Kim",
      "orcid": "0000-0003-2647-2690"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/cb8018v6g3nw4.bib",
  "cited_by": 1,
  "doi": "10.5187/jast.2500456",
  "fulltext_url": "https://europepmc.org/articles/PMC13678349",
  "id": "cb8018v6g3nw4",
  "issns": [
    "2055-0391"
  ],
  "landing_url": "https://europepmc.org/article/MED/42898589",
  "language": "eng",
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1103|Animal Nutrition and Physiology"
    ]
  ],
  "openalex": "W7162656543",
  "pdf_url": "https://europepmc.org/articles/PMC13678349?pdf=render",
  "pmcid": "PMC13678349",
  "pmid": "42898589",
  "published": "2026-09-30",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/cb8018v6g3nw4.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:37Z",
      "native_id": "MED:42898589",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42898589"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:1103|Animal Nutrition and Physiology",
      "subfield": "zoology-behaviour"
    }
  ],
  "title": "Nutritional strategies using synbiotics and organic acids to enhance piglet post-weaning growth and gut health.",
  "title_text": "Nutritional strategies using synbiotics and organic acids to enhance piglet post-weaning growth and gut health.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:19:37Z",
  "url": "https://research.draconitic.com/paper/cb8018v6g3nw4",
  "venue": "Journal of animal science and technology",
  "versions": []
}