{
  "abstract": "We report a simple revisited route to derivatize polysaccharides with molecular epoxides or epoxide-functionalized macromolecules in water at neutral pH, without a catalyst. Exploiting model reactions on monosaccharide derivatives, we show that the catalyst-free grafting of epoxides is feasible when performed on carboxylated polysaccharides. Using alginate and glycidyl methacrylate, a degree of substitution up to 0.31 can be achieved within 1 day. Thanks to the mild conditions of derivatization (moderate temperatures, neutral pH, no catalyst), this environmentally friendly strategy enables efficient synthesis of advanced polysaccharide-based architectures with chemically sensitive moieties. In line with this, we successfully obtained water-soluble alginate-g-poly(acrylamide-co-glycidyl methacrylate) hybrids, which are highly sought after for water treatment applications, by grafting short hydrophilic epoxide-and xanthate-functionalized poly(AM-co-GMA) copolymers, followed by reversible additionfragmentation chain transfer chain extension.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 12,
  "authors": [
    {
      "name": "Théo Pesenti"
    },
    {
      "name": "Mathieu Madau"
    },
    {
      "name": "Arthur Bouchut"
    },
    {
      "name": "Maria Tomczak"
    },
    {
      "name": "Agnès Crépet"
    },
    {
      "name": "Carlos Fernandez-De-Alba"
    },
    {
      "name": "Clément Coquery"
    },
    {
      "name": "Renaud Souzy"
    },
    {
      "name": "Olivier Braun"
    },
    {
      "name": "Etienne Fleury"
    },
    {
      "name": "Aurélia Charlot"
    },
    {
      "name": "Julien Bernard"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/cchcqmn0cgp2c.bib",
  "cited_by": 0,
  "doi": "10.1021/acsapm.6c01255",
  "fulltext_url": null,
  "id": "cchcqmn0cgp2c",
  "issns": [
    "2637-6105"
  ],
  "landing_url": "https://hal.science/hal-05799977v1",
  "language": "en",
  "licence": "CC-BY-NC-ND-4.0",
  "licence_label": "CC BY-NC-ND 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.chim"
    ],
    [
      "hal",
      "1.chim.poly"
    ],
    [
      "openalex",
      "1605|Advanced Polymer Synthesis and Characterization"
    ]
  ],
  "openalex": "W7167739192",
  "pdf_url": "https://hal.science/hal-05799977/document",
  "pmcid": null,
  "pmid": null,
  "published": "2026-07-08",
  "publisher": "American Chemical Society",
  "ris": "https://research.draconitic.com/paper/cchcqmn0cgp2c.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:57Z",
      "native_id": "hal-05799977",
      "source": "hal",
      "url": "https://hal.science/hal-05799977v1"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "hal:1.chim.poly",
      "subfield": "materials-polymers"
    }
  ],
  "title": "Aqueous Catalyst-Free Derivatization of Polysaccharides with Epoxides at Neutral pH",
  "title_text": "Aqueous Catalyst-Free Derivatization of Polysaccharides with Epoxides at Neutral pH",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:57Z",
  "url": "https://research.draconitic.com/paper/cchcqmn0cgp2c",
  "venue": "ACS Applied Polymer Materials",
  "versions": []
}