{
  "abstract": "Background: Congenital Pseudoarthrosis of the Tibia (CPT) is a rare condition characterized by poorly perfused, invasive hamartomatous fibrous tissue that leads to fracture and pseudoarthrosis of the tibia. Management challenges include achieving union and preventing refractures. This study aims to evaluate surgical interventions and their outcomes in managing congenital pseudoarthrosis of the tibia in children. Materials and methods: This retrospective study reviewed 70 CPT cases treated between 2010 and 2022 at Nepal’s only specialized center for children with physical disabilities. It assessed demographics, surgical procedures, and outcomes, with techniques including periosteal grafting and the Masquelet method. Union was defined radiologically, and analyses were conducted using MS Excel and SPSS. Results: This study included 70 CPT patients; 40 male (57.1%) and 30 female (42.9%). The mean age at presentation was 3.84 years, with the first surgery at 5.38 years. Most cases were Boyd type 5 (71.43%) and Crawford type 4 (71.43%). Of 35 patients who underwent surgery, the union rate was 41.93% (13/31), with a refracture rate of 23.08% among unions. Periosteal grafting had a 50% union rate, while the Masquelet technique achieved 41.67%. Conclusions: This study highlights the challenges in managing Congenital Pseudoarthrosis of the Tibia (CPT), emphasizing the need for personalized surgical approaches based on patient age, limb length discrepancy, and classification. Effective patient counseling on risks and benefits is crucial for informed decisions.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Orthopedics, Hospital and Rehabilitation Center for Disabled Children (HRDC), Janagal, Banepa, Nepal"
  ],
  "article_type": "Research Article",
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Tarun RajBhandari"
    },
    {
      "name": "Sabin Pokharel"
    },
    {
      "name": "Yam Prakash Gurung"
    },
    {
      "name": "Rajan Bhusal"
    },
    {
      "name": "Bibek Banskota"
    },
    {
      "name": "Ashok Kumar Banskota"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/ccy0q54jkyjbq.bib",
  "cited_by": 0,
  "doi": "10.1371/journal.pone.0362359",
  "fulltext_url": null,
  "id": "ccy0q54jkyjbq",
  "issns": [
    "1932-6203"
  ],
  "landing_url": "https://doi.org/10.1371/journal.pone.0362359",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "plos",
      "/Biology and life sciences/Anatomy/Body limbs"
    ],
    [
      "plos",
      "/Biology and life sciences/Anatomy/Body limbs/Legs/Ankles"
    ],
    [
      "plos",
      "/Biology and life sciences/Anatomy/Musculoskeletal system/Skeleton/Fibula"
    ],
    [
      "plos",
      "/Biology and life sciences/Anatomy/Musculoskeletal system/Skeleton/Tibia"
    ],
    [
      "plos",
      "/Medicine and health sciences/Anatomy/Body limbs"
    ],
    [
      "plos",
      "/Medicine and health sciences/Anatomy/Body limbs/Legs/Ankles"
    ],
    [
      "plos",
      "/Medicine and health sciences/Anatomy/Musculoskeletal system/Skeleton/Fibula"
    ],
    [
      "plos",
      "/Medicine and health sciences/Anatomy/Musculoskeletal system/Skeleton/Tibia"
    ],
    [
      "plos",
      "/Medicine and health sciences/Clinical genetics/Stem cell therapy"
    ],
    [
      "plos",
      "/Medicine and health sciences/Critical care and emergency medicine/Trauma medicine/Traumatic injury/Bone fracture"
    ],
    [
      "plos",
      "/Medicine and health sciences/Surgical and invasive medical procedures"
    ],
    [
      "plos",
      "/Medicine and health sciences/Surgical and invasive medical procedures/Surgical amputation"
    ]
  ],
  "openalex": null,
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-11-05",
  "publisher": "Public Library of Science",
  "ris": "https://research.draconitic.com/paper/ccy0q54jkyjbq.ris",
  "sources": [
    {
      "first_seen": "2026-11-06T12:20:42Z",
      "native_id": "10.1371/journal.pone.0362359",
      "source": "plos",
      "url": "https://doi.org/10.1371/journal.pone.0362359"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "plos:anatomy",
      "subfield": "physiology"
    }
  ],
  "title": "The surgical outcome among children with congenital pseudoarthrosis of Tibia: Our 12 years of experience",
  "title_text": "The surgical outcome among children with congenital pseudoarthrosis of Tibia: Our 12 years of experience",
  "type": "peer-reviewed",
  "updated_at": "2026-11-07T12:20:24Z",
  "url": "https://research.draconitic.com/paper/ccy0q54jkyjbq",
  "venue": "PLOS One",
  "versions": []
}