{
  "abstract": "Olfaction is crucial for insects adapting to agroecosystems and becoming significant crop pests, but how the antenna, a multicellular olfactory organ, is systematically organized at the cellular and molecular levels is not well understood. This study focuses on tephritids, particularly Bactrocera dorsalis, due to its global invasiveness and severe agricultural impact. We conducted comparative single‐nucleus transcriptomics of the antennal olfactory organ in B. dorsalis and Drosophila melanogaster, revealing uneven transcriptomic divergence across cell types: structural cells showed higher cross‐species similarity, while sensory neuronal populations and receptor expression were more divergent. Notably, in B. dorsalis, ammonia detection involves an additional candidate neuronal population with BdorAmt/BdorOrco transcript co‐detection, contrasting with D. melanogaster, where ammonia detection is mediated by Amt‐expressing neurons independently of Orco. This derived molecular sensing logic helps meet the ecological demands of B. dorsalis, in which females use ammonia as an important cue to locate bird droppings as a potential supplementary nutritional resource. Our results suggest that cell‐type‐dependent transcriptomic divergence may represent one important route through which insect olfactory systems adapt, with neuronal diversification contributing to molecular sensing pathways tailored to specific ecological demands.",
  "abstract_shown": true,
  "affiliations": [
    "Shenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Key Laboratory of Synthetic Biology, Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen Chinese Academy of Agricultural Sciences Shenzhen China",
    "State Key Laboratory of Plant Trait Design, Center For Excellence in Molecular Plant Sciences Chinese Academy of Sciences Shanghai China",
    "University of Chinese Academy of Sciences Beijing China",
    "Hubei Key Laboratory of Biological Resources Protection and Utilization, College of Forestry and Horticulture HuBei Min Zu University Enshi China",
    "School of Forestry, Key Laboratory of Sustainable Forest Ecosystem Management‐Ministry of Education Northeast Forestry University Harbin China",
    "Shanxi Key Laboratory of Efficient Cultivation of Forest Resources, College of Forestry Shanxi Agricultural University Jinzhong China"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 8,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Wei Liu",
      "orcid": "0000-0001-5852-2336"
    },
    {
      "affs": [
        1,
        2
      ],
      "name": "Shuai Zhang",
      "orcid": "0009-0001-4145-256X"
    },
    {
      "affs": [
        0,
        3
      ],
      "name": "Jie Zhang"
    },
    {
      "affs": [
        4
      ],
      "name": "Zhen Tian"
    },
    {
      "affs": [
        1,
        2
      ],
      "name": "Yuanbo Xue",
      "orcid": "0009-0006-3820-9266"
    },
    {
      "affs": [
        0,
        5
      ],
      "name": "Ling Yang"
    },
    {
      "affs": [
        1
      ],
      "name": "Jun Xu",
      "orcid": "0000-0002-7963-0253"
    },
    {
      "affs": [
        0
      ],
      "name": "Guirong Wang",
      "orcid": "0000-0002-3794-0106"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/ce8px1qm6ay7j.bib",
  "cited_by": 0,
  "doi": "10.1002/advs.77168",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13479590/",
  "id": "ce8px1qm6ay7j",
  "issns": [
    "2198-3844"
  ],
  "landing_url": "https://doi.org/10.1002/advs.77168",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Research Article"
    ],
    [
      "openalex",
      "2804|Neurobiology and Insect Physiology Research"
    ]
  ],
  "openalex": "W7203632966",
  "pdf_url": null,
  "pmcid": "PMC13479590",
  "pmid": "42605974",
  "published": "2026-08-17",
  "publisher": "Wiley",
  "ris": "https://research.draconitic.com/paper/ce8px1qm6ay7j.ris",
  "sources": [
    {
      "first_seen": "2026-11-11T12:22:34Z",
      "native_id": "PMC13479590",
      "source": "pmc",
      "url": "https://doi.org/10.1002/advs.77168"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:2804|Neurobiology and Insect Physiology Research",
      "subfield": "neuroscience"
    }
  ],
  "title": "Asymmetric Evolution of Antennal Cell Types Underlies a Derived Ammonia‐Sensing Logic for Ecological Adaptation in Bactrocera dorsalis",
  "title_text": "Asymmetric Evolution of Antennal Cell Types Underlies a Derived Ammonia‐Sensing Logic for Ecological Adaptation in Bactrocera dorsalis",
  "type": "peer-reviewed",
  "updated_at": "2026-11-13T12:20:16Z",
  "url": "https://research.draconitic.com/paper/ce8px1qm6ay7j",
  "venue": "Advanced Science",
  "versions": []
}