{
  "abstract": "Tuberous sclerosis complex (TSC) is a multisystem genetic disorder in which cardiac rhabdomyomas and myocardial fatty foci are recognized cardiac manifestations, whereas discrete cardiac lipoma-like masses are uncommon. We report a 42-year-old woman with genetically and clinically confirmed TSC who underwent contrast-enhanced chest CT for surveillance of pulmonary lymphangioleiomyomatosis. CT demonstrated a well-circumscribed homogeneous macroscopic-fat attenuation mass centered in the mid-to-apical interventricular septum, measuring 2.8 × 2.2 × 2.0 cm with mean attenuation of approximately -92 HU and mild contour bulging toward the right ventricular cavity. The discrete mass-like morphology and homogeneous macroscopic fat favored cardiac lipoma over a typical TSC-associated myocardial fatty focus, although definitive distinction remains limited in the absence of dedicated cardiac MRI or histopathologic confirmation. This case emphasizes the imaging differential of fat-containing myocardial lesions in adults with TSC and the importance of integrating lesion morphology, size, tissue composition, and mass effect rather than relying on septal location alone.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Radiology, University of Iowa Hospitals & Clinics, Iowa City, IA, USA.",
    "Department of Pediatrics, University of Connecticut, Hartford, CT, USA."
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Saubhagya Dhakal"
    },
    {
      "affs": [
        0
      ],
      "name": "Paulo Savoia",
      "orcid": "0000-0002-0983-1930"
    },
    {
      "affs": [
        0
      ],
      "name": "Nikahat Yasmine"
    },
    {
      "affs": [
        1
      ],
      "name": "Manisha Sharma"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/cf2qrnm6j7dhf.bib",
  "cited_by": 0,
  "doi": "10.1016/j.radcr.2026.09.027",
  "fulltext_url": "https://europepmc.org/articles/PMC13684998",
  "id": "cf2qrnm6j7dhf",
  "issns": [
    "1930-0433"
  ],
  "landing_url": "https://europepmc.org/article/MED/42909378",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2737|Tuberous Sclerosis Complex Research"
    ]
  ],
  "openalex": "W7221628960",
  "pdf_url": "https://europepmc.org/articles/PMC13684998?pdf=render",
  "pmcid": "PMC13684998",
  "pmid": "42909378",
  "published": "2026-10-13",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/cf2qrnm6j7dhf.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:20:10Z",
      "native_id": "MED:42909378",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42909378"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2737|Tuberous Sclerosis Complex Research",
      "subfield": "physiology"
    }
  ],
  "title": "Interventricular septal fat-containing mass most consistent with cardiac lipoma in an adult with tuberous sclerosis complex.",
  "title_text": "Interventricular septal fat-containing mass most consistent with cardiac lipoma in an adult with tuberous sclerosis complex.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:20:10Z",
  "url": "https://research.draconitic.com/paper/cf2qrnm6j7dhf",
  "venue": "Radiology case reports",
  "versions": []
}