{
  "abstract": "Rationale : High-throughput MALDI-MS analyses produce extensive datasets daily. Each spectrum obtained from a complex mixture of oligosaccharides, generated through the enzymatic digestion of polymeric carbohydrates, can contain a vast amount of information requiring processing. Therefore, the availability of specialized informatics tools to facilitate data interpretation is essential. Methods : SugarMALDI is introduced as a cloud-based platform designed to support MALDI-MS interpretation of oligosaccharides. It enables the identification of both labeled and unlabeled oligosaccharides in complex MALDI-MS spectra, facilitates molecular formula assignment, and assesses candidate matches according to mass accuracy. Users can select from nine elemental monosaccharides available in the database, as well as define ionization adducts and chemical modifications, and modify parameters, allowing the software to be flexibly tailored to specific analytical contexts. Results : Designed for high-throughput workflows, the platform accelerates data processing while ensuring reliable interpretation. It was successfully validated using enzymatically digested standard plant gums, including arabinogalactan and galactomannan, as well as authentic watercolor samples, confirming its robustness and practical relevance. The average execution time was approximately two minutes per file, increasing proportionally with the number of selected monosaccharides. These results highlight the software’s efficiency, adaptability, and suitability for diverse analytical applications. Conclusions : SugarMALDI provides assisted data interpretation tailored to the needs of glycobiologists and glycochemists. It supports structural and compositional characterization, enables polysaccharide identification, and delivers clear visual reporting of results, thereby streamlining analysis and enhancing the efficiency and reliability of glycomic investigations.",
  "abstract_shown": true,
  "affiliations": [
    "l’Analyse et la Protéomique, MSAP, Miniaturisation pour la Synthèse, Lille, France, F-59000",
    "CNRS Institut CARMeN UMR",
    "Shrieking sixties",
    "Institut Pasteur"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Pierre-Alexandre Ho"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Christian Rolando"
    },
    {
      "affs": [
        0,
        3
      ],
      "name": "Marie Yammine",
      "orcid": "0000-0001-6772-313X"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/cfpgztyc81ejy.bib",
  "cited_by": 0,
  "doi": "10.26434/chemrxiv.15008457/v1",
  "fulltext_url": null,
  "id": "cfpgztyc81ejy",
  "issns": [],
  "landing_url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15008457/v1",
  "language": null,
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1607|Mass Spectrometry Techniques and Applications"
    ]
  ],
  "openalex": "W7211929638",
  "pdf_url": "https://chemrxiv.org/doi/pdf/10.26434/chemrxiv.15008457/v1",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-07",
  "publisher": "American Chemical Society (ACS)",
  "ris": "https://research.draconitic.com/paper/cfpgztyc81ejy.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:17Z",
      "native_id": "10.26434/chemrxiv.15008457",
      "source": "chemrxiv",
      "url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15008457/v1"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1607|Mass Spectrometry Techniques and Applications",
      "subfield": "physical"
    }
  ],
  "title": "SugarMALDI: An Application for oligosaccharides’ identification in MALDI-MS data",
  "title_text": "SugarMALDI: An Application for oligosaccharides’ identification in MALDI-MS data",
  "type": "preprint",
  "updated_at": "2026-10-30T12:17:17Z",
  "url": "https://research.draconitic.com/paper/cfpgztyc81ejy",
  "venue": "ChemRxiv",
  "versions": []
}