{
  "abstract": "AIM: To evaluate the efficacy and safety of scleral lenses (SLs) in patients with keratoconus. METHODS: Electronic databases including PubMed, Scopus, Web of Science, Embase, and Cochrane Library were systematically searched to find the articles on visual function and patient satisfaction following SLs fitting. A random-effects model was applied to specify the pooled values. RESULTS: Of 833 studies, 19 articles (704 eyes) and 14 studies (475 eyes) were included in qualitative and quantitative synthesis, respectively. Pooled mean difference (PMD) of best corrected visual acuity (BCVA) was -0.37 [95% confidence interval (CI), -0.48 to -0.26] logMAR in favor of SLs treatment. SLs markedly reduced ocular and corneal higher-order aberrations and increased the quality of vision. The overall pooled values for comfort, visual quality and patient satisfaction with SLs were 4.19 (95%CI, 3.83 to 4.55), 4.30 (95%CI, 3.97 to 4.64), and 80.83% (95%CI, 71.54% to 90.13%), respectively. The most reported complications were lens breakage (26.1%) and conjunctival injection (11.4%-15.8%). CONCLUSION: SLs fitting leads to improved visual outcomes and patient satisfaction in patients with keratoconus.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Optometry, School of Rehabilitation Sciences, Shahid Beheshti University of Medical Sciences, Tehran 16169-13111, Iran",
    "Proteomics Research Center, Department of Biostatistics, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran 19716-53313, Iran"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Mojgan Pakbin"
    },
    {
      "affs": [
        0
      ],
      "name": "Maryam Dashti"
    },
    {
      "affs": [
        1
      ],
      "name": "Ali Reza Akbarzadeh Baghban"
    },
    {
      "affs": [
        0
      ],
      "name": "Haleh Kangari"
    },
    {
      "affs": [
        0
      ],
      "name": "Ali Ayatollahi"
    },
    {
      "affs": [
        0
      ],
      "name": "Mohammad Ghassemi-Broumand"
    },
    {
      "affs": [
        0
      ],
      "name": "Saeed Rahmani"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/cgncrdx5rc1r0.bib",
  "cited_by": 0,
  "doi": "10.18240/ijo.2026.11.17",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13717368/",
  "id": "cgncrdx5rc1r0",
  "issns": [
    "2222-3959",
    "2227-4898"
  ],
  "landing_url": "https://doi.org/10.18240/ijo.2026.11.17",
  "language": "en",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Meta-Analysis"
    ],
    [
      "openalex",
      "2741|Corneal surgery and disorders"
    ]
  ],
  "openalex": "W7223047533",
  "pdf_url": "https://gjyk.ijournals.cn//gjyken/article/pdf/20261117",
  "pmcid": "PMC13717368",
  "pmid": "42959447",
  "published": "2026-11-02",
  "publisher": "Press of International Journal of Ophthalmology",
  "ris": "https://research.draconitic.com/paper/cgncrdx5rc1r0.ris",
  "sources": [
    {
      "first_seen": "2026-11-02T12:21:42Z",
      "native_id": "PMC13717368",
      "source": "pmc",
      "url": "https://doi.org/10.18240/ijo.2026.11.17"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "heading:Meta-Analysis",
      "subfield": "clinical-trials"
    }
  ],
  "title": "Clinical outcomes of scleral lenses in keratoconus: a systematic review and Meta-analysis",
  "title_text": "Clinical outcomes of scleral lenses in keratoconus: a systematic review and Meta-analysis",
  "type": "peer-reviewed",
  "updated_at": "2026-11-02T12:21:42Z",
  "url": "https://research.draconitic.com/paper/cgncrdx5rc1r0",
  "venue": "International Journal of Ophthalmology",
  "versions": []
}