{
  "abstract": "While the immuno-modulatory effects of lactic acid bacteria (LAB) on conventional T cells are well documented, their effects on unconventional T cells, including gamma-delta (γδ) T cells, have not yet been fully characterized. Here, we show that LAB can generate regulatory γδ T cells by significantly increasing interleukin (IL)-10 production relative to stimulation with methicillin-resistant Staphylococcus aureus (MRSA), a pathogenic bacterial strain. This regulatory function subsequently attenuated inflammatory responses in intestinal epithelial cells and immune cells. Thus, LAB can induce regulatory functions in γδ T cells, which may contribute to the maintenance of intestinal health.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "name": "Zhenzi PENG"
    },
    {
      "name": "Alato OKUNO"
    },
    {
      "name": "Suguru SAITO"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/chpfac1jrafdb.bib",
  "cited_by": 0,
  "doi": "10.12938/bmfh.2025-092",
  "fulltext_url": "https://www.jstage.jst.go.jp/article/bmfh/advpub/0/advpub_2025-092/_article",
  "id": "chpfac1jrafdb",
  "issns": [
    "2186-3342"
  ],
  "landing_url": "https://www.jstage.jst.go.jp/article/bmfh/advpub/0/advpub_2025-092/_article",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "jstage-journal",
      "biology/microbiology"
    ],
    [
      "openalex",
      "1106|Probiotics and Fermented Foods"
    ]
  ],
  "openalex": "W7212130152",
  "pdf_url": "https://www.jstage.jst.go.jp/article/bmfh/advpub/0/advpub_2025-092/_pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-11",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/chpfac1jrafdb.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:35Z",
      "native_id": "10.12938/bmfh.2025-092",
      "source": "jstage",
      "url": "https://www.jstage.jst.go.jp/article/bmfh/advpub/0/advpub_2025-092/_article"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "jstage-journal:biology/microbiology",
      "subfield": "microbiology"
    }
  ],
  "title": "Lactic acid bacteria induce regulatory functions in γδ T cells",
  "title_text": "Lactic acid bacteria induce regulatory functions in γδ T cells",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:35Z",
  "url": "https://research.draconitic.com/paper/chpfac1jrafdb",
  "venue": "Bioscience of Microbiota, Food and Health",
  "versions": []
}