{
  "abstract": "We report the first catalytic phosphorus-based hydrogen atom transfer system. Using an iridium photocatalyst and 10 mol% diphenylphosphine sulfide, we achieve decarboxylative reduction of diverse carboxylic acids—including peptides and pharmaceuticals—to C–H products in up to 95% yield, without stoichiometric reductants. Mechanistic studies reveal an unprecedented anionic relay: a phosphoryl radical is reduced to a phosphinoyl anion, which upon protonation regenerates the P–H catalyst. This work establishes catalytic turnover in phosphorus-based HAT and identifies a new elementary step in main-group radical chemistry.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "name": "Pratik Avinash"
    },
    {
      "name": "Kayla Merrigan"
    },
    {
      "name": "Bartosz Bieszczad",
      "orcid": "0000-0002-9503-0792"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/cmfe8b1sxsf2w.bib",
  "cited_by": 0,
  "doi": "10.26434/chemrxiv.15008559/v1",
  "fulltext_url": null,
  "id": "cmfe8b1sxsf2w",
  "issns": [],
  "landing_url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15008559/v1",
  "language": null,
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1605|Radical Photochemical Reactions"
    ]
  ],
  "openalex": "W7212041338",
  "pdf_url": "https://chemrxiv.org/doi/pdf/10.26434/chemrxiv.15008559/v1",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-09",
  "publisher": "American Chemical Society (ACS)",
  "ris": "https://research.draconitic.com/paper/cmfe8b1sxsf2w.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:19Z",
      "native_id": "10.26434/chemrxiv.15008559",
      "source": "chemrxiv",
      "url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15008559/v3"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1605|Radical Photochemical Reactions",
      "subfield": "organic"
    }
  ],
  "title": "Catalytic Phosphorus-Based Hydrogen Atom",
  "title_text": "Catalytic Phosphorus-Based Hydrogen Atom",
  "type": "preprint",
  "updated_at": "2026-11-06T00:20:51Z",
  "url": "https://research.draconitic.com/paper/cmfe8b1sxsf2w",
  "venue": "ChemRxiv",
  "versions": []
}