{
  "abstract": "Respiratory syncytial virus (RSV) infects nearly all children under 2 years of age and poses a significant risk, particularly for infants younger than 6 months. Since 2025, pregnant women in Poland have been eligible for free vaccination against RSV. The aim of this study was to evaluate the concentration of anti-RSV IgG antibodies (types A and B) in vaccinated pregnant women at delivery and in umbilical cord blood of their newborns. Anti-RSV IgG levels were measured using the ELISA method in 304 paired maternal and cord blood samples. Vaccination was administered at 27 to 39 weeks of gestation (mean = 32 weeks). Significantly higher concentrations of IgG antibodies were observed in newborns compared to their mothers ( p < 0.0001), with no association with neonatal sex ( p = 0.41). No correlation was found between the interval from maternal vaccination to delivery and antibody levels in either maternal or cord blood. A history of RSV infection in older children did not result in a statistically significant increase in anti-RSV IgG levels in either mothers or newborns. Conclusions: Maternal RSV vaccination, optimally administered during the third trimester, provides effective passive immunity to the newborn through active transplacental antibody transfer. Vaccination should be recommended during each subsequent pregnancy.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Obstetrics, Gynecology and Oncology of The Provincial Hospital named after L. Rydygier in Toruń, Poland; Corresponding author.",
    "Department of Obstetrics, Gynecology and Oncology of The Provincial Hospital named after L. Rydygier in Toruń, Poland; Academy of Applied Medical and Social Sciences, Elbląg, Poland",
    "Department of Obstetrics, Gynecology and Oncology of The Provincial Hospital named after L. Rydygier in Toruń, Poland"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Szymon Bednarek"
    },
    {
      "affs": [
        1
      ],
      "name": "Małgorzata Świątkowska-Freund"
    },
    {
      "affs": [
        2
      ],
      "name": "Grażyna Misiak"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/cnw75bekp5c0r.bib",
  "cited_by": 0,
  "doi": "10.1016/j.jvacx.2026.100923",
  "fulltext_url": "http://www.sciencedirect.com/science/article/pii/S2590136226001464",
  "id": "cnw75bekp5c0r",
  "issns": [
    "2590-1362"
  ],
  "landing_url": "https://doi.org/10.1016/j.jvacx.2026.100923",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "RC581-607"
    ],
    [
      "openalex",
      "2713|Respiratory viral infections research"
    ]
  ],
  "openalex": "W7221872031",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-30",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/cnw75bekp5c0r.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:44:51Z",
      "native_id": "20c55befb80444328a892b078ecdd263",
      "source": "doaj",
      "url": "https://doi.org/10.1016/j.jvacx.2026.100923"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2713|Respiratory viral infections research",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "Respiratory syncytial virus vaccination during pregnancy confers higher anti-RSV IgG concentration in neonatal cord than maternal blood",
  "title_text": "Respiratory syncytial virus vaccination during pregnancy confers higher anti-RSV IgG concentration in neonatal cord than maternal blood",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:44:51Z",
  "url": "https://research.draconitic.com/paper/cnw75bekp5c0r",
  "venue": "Vaccine: X",
  "versions": []
}