{
  "abstract": "Objective\n\nThe aim of this pilot study was to evaluate the preliminary efficacy and feasibility of integrating Osteopathic Manual Therapy Techniques combined with Clinical Pilates on pain, symptom severity, and sleep quality in patients with fibromyalgia.Methods\n\nTwenty women with fibromyalgia were randomized into Osteopathic Manual Therapy Techniques+Clinical Pilates (n=11) and Clinical Pilates (n=9) groups. The protocol lasted 6 weeks (3 sessions/week). Osteopathic Manual Therapy Techniques included rib raising, suboccipital myofascial release, Sternocleidomastoid (SCM) mobilization, diaphragm/mediastinum techniques, and visceral mobilizations. Primary outcomes were the Widespread Pain Index, Symptom Severity Scale, and Pressure Pain Threshold. Sleep was assessed via the Pittsburgh Sleep Quality Index.Results\n\nBoth groups showed significant intra-group improvements (p<0.05). Within-group analyses revealed that the Osteopathic Manual Therapy Techniques+Clinical Pilates group achieved significant improvements in Widespread Pain Index (p=0.003), Symptom Severity Scale (p=0.005), and Pittsburgh Sleep Quality Index (p=0.007). However, in the between-group analysis of change scores, the Osteopathic Manual Therapy Techniques+Clinical Pilates group demonstrated significantly superior improvements exclusively in sleep quality (Pittsburgh Sleep Quality Index, p=0.034) and maximal Pressure Pain Threshold at the trapezius (p=0.035) compared to the Clinical Pilates-only group, while between-group differences for Widespread Pain Index and Symptom Severity Scale did not reach statistical significance (p>0.05).Conclusion\n\nIntegrating Osteopathic Manual Therapy Techniques into exercise-based rehabilitation presents promising preliminary evidence for enhancing central sensitization symptoms and sleep quality in fibromyalgia patients, though larger trials are needed.",
  "abstract_shown": true,
  "affiliations": [
    "Gaziantep Islam Science and Technology University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation - Gaziantep, Türkiye.",
    "Usak University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation - Uşak, Türkiye.",
    "Siirt University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation - Siirt, Türkiye.",
    "Pamukkale University, Faculty of Physiotherapy and Rehabilitation, Department of Orthopedic Rehabilitation - Denizli, Türkiye.",
    "Pamukkale University, Faculty of Medicine, Department of Internal Medicine - Denizli, Türkiye."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Aziz Dengiz",
      "orcid": "0000-0003-3492-7448"
    },
    {
      "affs": [
        1
      ],
      "name": "Elif Gur Kabul",
      "orcid": "0000-0003-3209-1499"
    },
    {
      "affs": [
        2
      ],
      "name": "Gulsum Tikac",
      "orcid": "0000-0001-7375-6747"
    },
    {
      "affs": [
        3
      ],
      "name": "Bilge Basakci Calik",
      "orcid": "0000-0002-7267-7622"
    },
    {
      "affs": [
        4
      ],
      "name": "Uğur Karasu",
      "orcid": "0000-0003-0090-0247"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/cqhh211pk3abc.bib",
  "cited_by": 0,
  "doi": "10.1590/1806-9282.20260646",
  "fulltext_url": "https://europepmc.org/articles/PMC13661034",
  "id": "cqhh211pk3abc",
  "issns": [
    "0104-4230",
    "1806-9282"
  ],
  "landing_url": "https://europepmc.org/article/MED/42879584",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2738|Fibromyalgia and Chronic Fatigue Syndrome Research"
    ]
  ],
  "openalex": "W7222730887",
  "pdf_url": "https://europepmc.org/articles/PMC13661034?pdf=render",
  "pmcid": "PMC13661034",
  "pmid": "42879584",
  "published": "2026-10-12",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/cqhh211pk3abc.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:00Z",
      "native_id": "MED:42879584",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42879584"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2738|Fibromyalgia and Chronic Fatigue Syndrome Research",
      "subfield": "psychiatry"
    }
  ],
  "title": "Osteopathic manual therapy in fibromyalgia: a pilot study.",
  "title_text": "Osteopathic manual therapy in fibromyalgia: a pilot study.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:19:00Z",
  "url": "https://research.draconitic.com/paper/cqhh211pk3abc",
  "venue": "Revista da Associacao Medica Brasileira (1992)",
  "versions": []
}