{
  "abstract": "Paediatric dental patients are particularly vulnerable to inadvertent soft-tissue injury following local anaesthesia (LA) This preliminary study evaluated. the clinical efficacy of 810-nm diode laser photobiomodulation (PBM) in reversing oral soft-tissue anaesthesia in paediatric patients. Thirty-four children aged 8–12 years requiring bilateral primary toothextractions under infiltration LA were enrolled in by consideration of ethical codes. Local anaesthesia was administered using 2% lidocaine with 1:80,000 epinephrine, as per the local infiltration anesthesia protocol. Participants were randomly allocated to receive both PBM and sham Laser with 7-10 days washout period between the two interventions. PBM was delivered using an 810-nm diode laser in continuous mode at 200 mW for 12 s per point at six predefined intraoral and extraoral sites. An independent examiner assessed soft-tissue sensation at 5-minute intervals by standardized bilateral palpation, using the non-anaesthetized side as the reference. The primary outcome was time to first assessment at which sensation on the anaesthetized side was judged normal. Data were analysed using a paired-samples t-test. Mean reflection time was significantly shorter in the PBM group (60.7 ± 27.3 min; p < 0.001) compared with the Sham lasergroup (78.2 ± 17.0 min). Subgroup analysis demonstrated significant reductions in reflection time in both maxillary and mandibular arches. Photobiomodulation using an 810-nm diode laser demonstrated a reduction in subjective soft tissue anaesthesia recovery time following infiltration LA in paediatric dental patients under the conditions tested.\n\nSupplementary Information: The online version contains supplementary material available at https://doi.org/10.1007/s10103-026-05056-3.",
  "abstract_shown": true,
  "affiliations": [
    "Vishnu dental college, Bhimavaram, Andhra pradesh, India, India",
    "University at Buffalo, State University of New York, Buffalo, NY USA"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Zia Ul Haque Mohamed"
    },
    {
      "affs": [
        0
      ],
      "name": "Penmetsa Ahalya",
      "orcid": "0000-0001-5806-5032"
    },
    {
      "affs": [
        0
      ],
      "name": "Chandrappa Vinay",
      "orcid": "0000-0003-2607-297X"
    },
    {
      "affs": [
        0
      ],
      "name": "Peddi Ravigna"
    },
    {
      "affs": [
        1
      ],
      "name": "Praveen Arany",
      "orcid": "0000-0002-6116-2340"
    },
    {
      "affs": [
        0
      ],
      "name": "KS Uloopi",
      "orcid": "0000-0002-3477-0340"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/cs746fs7gra23.bib",
  "cited_by": 0,
  "doi": "10.1007/s10103-026-05056-3",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13714059/",
  "id": "cs746fs7gra23",
  "issns": [
    "0268-8921",
    "1435-604X"
  ],
  "landing_url": "https://doi.org/10.1007/s10103-026-05056-3",
  "language": "en",
  "licence": "CC-BY-NC-ND-4.0",
  "licence_label": "CC BY-NC-ND 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Research"
    ],
    [
      "openalex",
      "2741|Laser Applications in Dentistry and Medicine"
    ]
  ],
  "openalex": "W7223920538",
  "pdf_url": "https://link.springer.com/content/pdf/10.1007/s10103-026-05056-3.pdf",
  "pmcid": "PMC13714059",
  "pmid": "42946902",
  "published": "2026-10-28",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/cs746fs7gra23.ris",
  "sources": [
    {
      "first_seen": "2026-11-01T12:21:37Z",
      "native_id": "PMC13714059",
      "source": "pmc",
      "url": "https://doi.org/10.1007/s10103-026-05056-3"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2741|Laser Applications in Dentistry and Medicine",
      "subfield": "imaging"
    }
  ],
  "title": "Effect of photobiomodulation on recovery from oral soft tissue local anaesthesia in paediatric patients: a preliminary split-mouth randomized clinical trial",
  "title_text": "Effect of photobiomodulation on recovery from oral soft tissue local anaesthesia in paediatric patients: a preliminary split-mouth randomized clinical trial",
  "type": "peer-reviewed",
  "updated_at": "2026-11-01T12:21:37Z",
  "url": "https://research.draconitic.com/paper/cs746fs7gra23",
  "venue": "Lasers in Medical Science",
  "versions": []
}