{
  "abstract": "Purpose: Assess the feasibility of a 6-month individualized nutrition counseling and exercise program targeting a 10% body weight loss in breast cancer (BC) survivors, with secondary endpoints assessing metabolic parameters, cardiovascular function, and quality of life. Methods: This single-arm pilot study enrolled BC survivors with body mass index (BMI) ≥ 25 kg/m2 in a counseling program with a registered dietitian, consisting of in-person and telephone visits over six months. Outcomes measured included weight, body composition, blood markers, cardiovascular function, and quality of life at 3 and 6 months. Results: A total of 78 breast cancer survivors were enrolled; 59 remained in the study at Month 3, and 54 completed the 6-month follow-up. The median age of participants was 58.5 years, and the cohort was predominantly White (72.4%). Among the 54 participants who completed 6-month follow-up, 11.1% achieved >10% weight loss and 29.6% achieved >5% weight loss. At 3 months, significant reductions were observed in BMI, body fat composition, and hemoglobin A1c (HbA1c), along with improvements in quality of life, depression, and anxiety. At 6 months, significant reductions were observed in weight, BMI, and body fat composition, with improvements in quality of life and depressive symptoms. Conclusions: This hybrid nutrition and exercise program was associated with observed improvements in weight loss and improved quality of life among BC survivors. Implications for Cancer Survivors: A low-burden, hybrid nutrition and exercise program integrated into routine oncology follow-up may help breast cancer survivors achieve weight loss while improving their quality of life.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Hematology-Oncology, Maroone Cancer Center, Cleveland Clinic Florida, Weston, FL 33331, USA",
    "Department of Clinical Research, Cleveland Clinic Florida, Weston, FL 33331, USA"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 14,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Shashi Kant",
      "orcid": "0009-0007-3186-3887"
    },
    {
      "affs": [
        0
      ],
      "name": "Ahmad Alhalabi"
    },
    {
      "affs": [
        0
      ],
      "name": "Nadeem Bilani",
      "orcid": "0000-0002-7335-9319"
    },
    {
      "affs": [
        0
      ],
      "name": "Iktej Singh Jabbal",
      "orcid": "0000-0001-8991-7445"
    },
    {
      "affs": [
        0
      ],
      "name": "María Herrán"
    },
    {
      "affs": [
        0
      ],
      "name": "Theresa Abdo",
      "orcid": "0009-0007-0703-1319"
    },
    {
      "affs": [
        0
      ],
      "name": "Saad Sabbagh",
      "orcid": "0000-0001-5203-1050"
    },
    {
      "affs": [
        1
      ],
      "name": "Kaylee Sarna",
      "orcid": "0000-0003-3533-111X"
    },
    {
      "affs": [
        0
      ],
      "name": "Amanda Stevenson"
    },
    {
      "affs": [
        0
      ],
      "name": "Diana Saravia"
    },
    {
      "affs": [
        0
      ],
      "name": "Candice Schwartz"
    },
    {
      "affs": [
        0
      ],
      "name": "Thomas Samuel"
    },
    {
      "affs": [
        0
      ],
      "name": "Zeina Nahleh"
    },
    {
      "affs": [
        0
      ],
      "name": "Elizabeth Stone"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/ct3z63a5qvt1d.bib",
  "cited_by": 0,
  "doi": "10.3390/cancers18193198",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13664228/?tool=EBI",
  "id": "ct3z63a5qvt1d",
  "issns": [
    "2072-6694"
  ],
  "landing_url": "https://europepmc.org/article/PMC/PMC13664228",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2730|Cancer survivorship and care"
    ]
  ],
  "openalex": "W7220389471",
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13664228/pdf/?tool=EBI",
  "pmcid": "PMC13664228",
  "pmid": null,
  "published": "2026-10-01",
  "publisher": "MDPI AG",
  "ris": "https://research.draconitic.com/paper/ct3z63a5qvt1d.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:35Z",
      "native_id": "PMC:PMC13664228",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13664228"
    },
    {
      "first_seen": "2026-10-30T12:19:58Z",
      "native_id": "10.3390/cancers18193198",
      "source": "crossref",
      "url": "https://www.mdpi.com/2072-6694/18/19/3198"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2730|Cancer survivorship and care",
      "subfield": "oncology"
    }
  ],
  "title": "Quality-of-Life and Weight Loss Outcomes Following an Individualized Nutrition and Physical Activity Counseling Program in Breast Cancer Survivors: A Prospective Single-Arm Pilot Study",
  "title_text": "Quality-of-Life and Weight Loss Outcomes Following an Individualized Nutrition and Physical Activity Counseling Program in Breast Cancer Survivors: A Prospective Single-Arm Pilot Study",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:19:58Z",
  "url": "https://research.draconitic.com/paper/ct3z63a5qvt1d",
  "venue": "Cancers",
  "versions": []
}