{
  "abstract": "We show that the p53-Mdm2 gene interaction can be understood as a form of antithetic feedback, but with mixed feedback loops. In particular, we show that this viewpoint sheds light on the emergence and robustness properties of p53's oscillatory behaviour, as observed experimentally.",
  "abstract_shown": true,
  "affiliations": [
    "KTH Royal Institute of Technology"
  ],
  "article_type": "New results",
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "W. Jongeneel"
    },
    {
      "name": "M. Scolamiero"
    },
    {
      "name": "K. H. Johansson"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/cwbx2czg0p2xm.bib",
  "cited_by": 0,
  "doi": "10.64898/2026.10.04.756583",
  "fulltext_url": "https://www.biorxiv.org/content/10.64898/2026.10.04.756583v1.full",
  "id": "cwbx2czg0p2xm",
  "issns": [],
  "landing_url": "https://www.biorxiv.org/content/10.64898/2026.10.04.756583v1",
  "language": null,
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "biorxiv",
      "synthetic biology"
    ],
    [
      "openalex",
      "2730|Cancer-related Molecular Pathways"
    ]
  ],
  "openalex": "W7220721125",
  "pdf_url": "https://www.biorxiv.org/content/10.64898/2026.10.04.756583v1.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-04",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/cwbx2czg0p2xm.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:26:11Z",
      "native_id": "10.64898/2026.10.04.756583",
      "source": "biorxiv",
      "url": "https://www.biorxiv.org/content/10.64898/2026.10.04.756583v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "biorxiv:synthetic biology",
      "subfield": "systems-synthetic"
    }
  ],
  "title": "The p53-Mdm2 interaction through the lens of antithetic feedback",
  "title_text": "The p53-Mdm2 interaction through the lens of antithetic feedback",
  "type": "preprint",
  "updated_at": "2026-10-30T12:26:11Z",
  "url": "https://research.draconitic.com/paper/cwbx2czg0p2xm",
  "venue": "bioRxiv",
  "versions": []
}